Reactome | Syndecan-1 binds Integrins alpha2beta1, (alpha6beta4)

Schema > Reaction > Entries

Syndecan-1 binds Integrins alpha2beta1, (alpha6beta4) Show undefined attributes

authored	[InstanceEdit:2426268] Jupe, S, 2012-07-31
category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:2731117] Jupe, S, 2012-12-05
dbId	2731074
displayName	Syndecan-1 binds Integrins alpha2beta1, (alpha6beta4)
edited	[InstanceEdit:3318356] Jupe, S, 2013-04-26
eventOf	[Pathway:R-HSA-3000170] Syndecan interactions - Homo sapiens
input	[CandidateSet:R-HSA-2731104] Integrin alpha2beta1, (alpha6beta4) [plasma membrane] [DefinedSet:R-HSA-2684506] Syndecan-1 [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:2684483] Laminin alpha1 chain LG4 module promotes cell attachment through syndecans and cell spreading through integrin alpha2beta1 [LiteratureReference:2684503] The short arm of laminin gamma2 chain of laminin-5 (laminin-332) binds syndecan-1 and regulates cellular adhesion and migration by suppressing phosphorylation of integrin beta4 chain [LiteratureReference:2684478] The syndecan-1 ectodomain regulates alphavbeta3 integrin activity in human mammary carcinoma cells
modified	[InstanceEdit:10740525] Wright, Adam, 2024-03-08
name	Syndecan-1 binds Integrins alpha2beta1, (alpha6beta4)
orthologousEvent	[Reaction:R-CEL-2731074] Syndecan-1 binds Integrins alpha2beta1, (alpha6beta4) - Caenorhabditis elegans [Reaction:R-DME-2731074] Syndecan-1 binds Integrins alpha2beta1, (alpha6beta4) - Drosophila melanogaster [Reaction:R-GGA-2731074] Syndecan-1 binds Integrins alpha2beta1, (alpha6beta4) - Gallus gallus [Reaction:R-XTR-2731074] Syndecan-1 binds Integrins alpha2beta1, (alpha6beta4) - Xenopus tropicalis [Reaction:R-SSC-2731074] Syndecan-1 binds Integrins alpha2beta1, (alpha6beta4) - Sus scrofa [Reaction:R-BTA-2731074] Syndecan-1 binds Integrins alpha2beta1, (alpha6beta4) - Bos taurus [Reaction:R-CFA-2731074] Syndecan-1 binds Integrins alpha2beta1, (alpha6beta4) - Canis familiaris [Reaction:R-RNO-2731074] Syndecan-1 binds Integrins alpha2beta1, (alpha6beta4) - Rattus norvegicus [Reaction:R-MMU-2731074] Syndecan-1 binds Integrins alpha2beta1, (alpha6beta4) - Mus musculus
output	[Complex:R-HSA-2731084] Syndecan-1:Integrin alpha2beta1 (alpha6beta4) [plasma membrane]
releaseDate	2013-06-11
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:3597658] Fuentes, Ernesto, 2013-05-22 [InstanceEdit:3597676] Ricard-Blum, Sylvie, 2013-05-22
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-2731074
summation	[Summation:2731105] Syndecans have attached heparan sulfate (HS) and to a lesser...

Referrals

(hasEvent)

[Pathway:R-HSA-3000170] Syndecan interactions