Reactome | Ser-tRNA(Sec) is phosphorylated to Sep-tRNA(Sec) by PSTK

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Ser-tRNA(Sec) is phosphorylated to Sep-tRNA(Sec) by PSTK Show undefined attributes

authored	[InstanceEdit:5422928] Williams, MG, 2014-05-06
catalystActivity	[CatalystActivity:5359089] seryl-selenocysteinyl-tRNA kinase activity of PSTK:Mg2+ [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:2408534] Williams, MG, 2012-07-17
dbId	2408507
displayName	Ser-tRNA(Sec) is phosphorylated to Sep-tRNA(Sec) by PSTK
edited	[InstanceEdit:6793109] D'Eustachio, Peter, 2015-08-29
eventOf	[Pathway:R-HSA-2408557] Selenocysteine synthesis - Homo sapiens
followingEvent	[Reaction:R-HSA-2408555] Sep-tRNA(Sec) is converted to Sec-tRNA(Sec) by PXLP-K284-SEPSECS tetramer - Homo sapiens
inferredFrom	[Reaction:R-MMU-2408505] Ser-tRNA(Sec) is phosphorylated to Sep-tRNA(Sec) by Pstk - Mus musculus
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [GenomeEncodedEntity:R-HSA-5357730] Ser-tRNA(Sec) [cytosol]
isChimeric	false
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:5359299] Identification and characterization of phosphoseryl-tRNA[Ser]Sec kinase
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Ser-tRNA(Sec) is phosphorylated to Sep-tRNA(Sec) by PSTK
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [GenomeEncodedEntity:R-HSA-5357712] Sep-tRNA(Sec) [cytosol]
precedingEvent	[Reaction:R-HSA-2408526] tRNA(Sec) is serylated to Ser-tRNA(Sec) by SARS dimer - Homo sapiens
releaseDate	2015-12-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:6793106] Rush, MG, 2015-08-30
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-2408507
summation	[Summation:5359324] L-seryl-tRNA(Sec) kinase (PSTK) phosphorylates the serylated...

Referrals

(hasEvent)	[Pathway:R-HSA-2408557] Selenocysteine synthesis
(precedingEvent)	[Reaction:R-HSA-2408555] Sep-tRNA(Sec) is converted to Sec-tRNA(Sec) by PXLP-K284-SEPSECS tetramer
(inferredTo)	[Reaction:R-MMU-2408505] Ser-tRNA(Sec) is phosphorylated to Sep-tRNA(Sec) by Pstk

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