Reactome | FGFR3 point mutant dimers with enhanced kinase activity [plasma membrane]

Schema > CandidateSet > Entries

FGFR3 point mutant dimers with enhanced kinase activity [plasma membrane] Show undefined attributes

catalystActivities	[CatalystActivity:2033455] protein tyrosine kinase activity of FGFR3 point mutant dimers with enhanced kinase activity [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-HSA-2033485] Autocatalytic phosphorylation of FGFR3 point mutants with enhanced kinase activity - Homo sapiens
created	[InstanceEdit:2033384] Rothfels, K, 2012-01-09
dbId	2033383
disease	[Disease:1500689] cancer [Disease:2032940] bone development disease
displayName	FGFR3 point mutant dimers with enhanced kinase activity [plasma membrane]
hasCandidate	[Complex:R-HSA-2065831] FGFR3 A319E mutant dimer [plasma membrane] - Homo sapiens
hasMember	[Complex:R-HSA-2033337] FGFR3 G380R mutant dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-2033325] FGFR3 G382D mutant dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-2033332] FGFR3 K650E mutant dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-2033324] FGFR3 K650M mutant dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-2033336] FGFR3 K650N mutant dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-2033343] FGFR3 K650Q mutant dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-2033328] FGFR3 K650T mutant dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-2033342] FGFR3b G697C mutant dimer [plasma membrane] - Homo sapiens
inDisease	true
memberOf	[DefinedSet:R-HSA-2077412] FGFR3 mutant dimers [plasma membrane] - Homo sapiens
modified	[InstanceEdit:2065854] Rothfels, K, 2012-01-24
name	FGFR3 point mutant dimers with enhanced kinase activity
producedByEvent	[Reaction:R-HSA-2033476] Dimerization of FGFR3 point mutants with enhanced kinase activity - Homo sapiens
schemaClass	CandidateSet
species	[Species:48887] Homo sapiens
stId	R-HSA-2033383

Referrals

(output)	[Reaction:R-HSA-2033476] Dimerization of FGFR3 point mutants with enhanced kinase activity
(input)	[Reaction:R-HSA-2033485] Autocatalytic phosphorylation of FGFR3 point mutants with enhanced kinase activity
(diseaseEntity)	[EntityFunctionalStatus:5654461] gain_of_function of FGFR3 point mutant dimers with enhanced kinase activity [plasma membrane]
(physicalEntity)	[CatalystActivity:2033455] protein tyrosine kinase activity of FGFR3 point mutant dimers with enhanced kinase activity [plasma membrane]
(hasMember)	[DefinedSet:R-HSA-2077412] FGFR3 mutant dimers [plasma membrane]

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