Reactome | p-8Y-FGFR2 K660N [plasma membrane]

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p-8Y-FGFR2 K660N [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-2033312] Activated FGFR2 K660N mutant [plasma membrane] - Homo sapiens
created	[InstanceEdit:2033302] Rothfels, K, 2012-01-09
crossReference	[DatabaseIdentifier:2033259] COSMIC:COSV60655029
dbId	2033301
disease	[Disease:1500689] cancer [Disease:1614674] female reproductive endometrioid cancer [Disease:1625203] Crouzon syndrome [Disease:2032940] bone development disease
displayName	p-8Y-FGFR2 K660N [plasma membrane]
endCoordinate	821
hasModifiedResidue	[ModifiedResidue:2029853] O4'-phospho-L-tyrosine at unknown position [ModifiedResidue:2029853] O4'-phospho-L-tyrosine at unknown position [ModifiedResidue:2029853] O4'-phospho-L-tyrosine at unknown position [ModifiedResidue:2029853] O4'-phospho-L-tyrosine at unknown position [ModifiedResidue:2029853] O4'-phospho-L-tyrosine at unknown position [ModifiedResidue:2029853] O4'-phospho-L-tyrosine at unknown position [ModifiedResidue:2029853] O4'-phospho-L-tyrosine at unknown position [ModifiedResidue:2029853] O4'-phospho-L-tyrosine at unknown position [ReplacedResidue:1637907] L-lysine 660 replaced with L-asparagine
inDisease	true
literatureReference	[LiteratureReference:2033243] A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases
modified	[InstanceEdit:5649609] Rothfels, Karen, 2014-11-20
name	p-8Y-FGFR2 K660N
referenceEntity	[ReferenceGeneProduct:403305] UniProt:P21802 FGFR2
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-2033301
startCoordinate	22

Referrals

(hasComponent)

[Complex:R-HSA-2033312] Activated FGFR2 K660N mutant [plasma membrane]

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