Reactome | ERK5 activates the transcription factor MEF2

Schema > Reaction > Entries

authored	[InstanceEdit:188342] Nasi, Sergio, Annibali, D, 2006-10-10
catalystActivity	[CatalystActivity:199939] protein serine/threonine kinase activity of p-T218,Y220-MAPK7 [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:199916] Jassal, B, 2007-07-13 13:44:04
dbId	199929
displayName	ERK5 activates the transcription factor MEF2
eventOf	[Pathway:R-HSA-198753] ERK/MAPK targets - Homo sapiens
inferredFrom	[Reaction:R-RNO-199913] ERK5 activates the transcription factor MEF2 - Rattus norvegicus
input	[SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [DefinedSet:R-HSA-199911] MEF2 [nucleoplasm]
isInDisease	false
isInferred	true
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	ERK5 activates the transcription factor MEF2
output	[SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [DefinedSet:R-HSA-199933] p-MEF2 [nucleoplasm]
precedingEvent	[Reaction:R-HSA-198714] ERK5 translocates to the nucleus - Homo sapiens
releaseDate	2008-03-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:202668] Greene, LA, 2007-11-08 15:39:37
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-199929
summation	[Summation:199925] The MEF2 (Myocyte-specific enhancer factor 2) proteins const...

(hasEvent)	[Pathway:R-HSA-198753] ERK/MAPK targets
(inferredTo)	[Reaction:R-RNO-199913] ERK5 activates the transcription factor MEF2

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