Reactome | CSNK1A1 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

CSNK1A1 [cytosol] Show undefined attributes

catalystActivities	[CatalystActivity:5610635] protein serine/threonine kinase activity of CSNK1A1 [cytosol]
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-5339714] p-AXIN:GSK3 del304-316:CK1alpha:APC:PP2A:AMER1 complex [cytosol] - Homo sapiens [Complex:R-HSA-195250] AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] - Homo sapiens
consumedByEvent	[FailedReaction:R-HSA-4839746] Truncated AMER1 mutants destabilize the destruction complex - Homo sapiens [FailedReaction:R-HSA-4791278] APC truncation mutants have impaired AXIN binding - Homo sapiens [Reaction:R-HSA-195251] Assembly of the destruction complex - Homo sapiens [FailedReaction:R-HSA-4839734] AXIN mutants destabilize the destruction complex - Homo sapiens
created	[InstanceEdit:195266] Matthews, L, 2007-04-03 12:37:29
dbId	195263
displayName	CSNK1A1 [cytosol]
endCoordinate	337
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-195263] CSNK1A1 [cytosol] - Mus musculus [EntityWithAccessionedSequence:R-RNO-195263] CSNK1A1 [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-195263] CSNK1A1 [cytosol] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-195263] CSNK1A1 [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-SSC-195263] CSNK1A1 [cytosol] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-195263] CSNK1A1 [cytosol] - Danio rerio [EntityWithAccessionedSequence:R-GGA-195263] CSNK1A1 [cytosol] - Gallus gallus [EntityWithAccessionedSequence:R-DME-195263] CSNK1A1 [cytosol] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-195263] CSNK1A1 [cytosol] - Caenorhabditis elegans
memberOf	[CandidateSet:R-HSA-195284] CK1alpha (GSK3) [cytosol] - Homo sapiens
modified	[InstanceEdit:3772380] Rothfels, K, 2013-06-24
name	CSNK1A1 CK1alpha CSNK1A1
producedByEvent	[Reaction:R-HSA-201685] Beta-catenin is released from the destruction complex - Homo sapiens
referenceEntity	[ReferenceGeneProduct:57867] UniProt:P48729 CSNK1A1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-195263
startCoordinate	2

Referrals

(input)	[FailedReaction:R-HSA-4839734] AXIN mutants destabilize the destruction complex [FailedReaction:R-HSA-4839746] Truncated AMER1 mutants destabilize the destruction complex [FailedReaction:R-HSA-4791278] APC truncation mutants have impaired AXIN binding [Reaction:R-HSA-195251] Assembly of the destruction complex
(hasComponent)	[Complex:R-HSA-5339714] p-AXIN:GSK3 del304-316:CK1alpha:APC:PP2A:AMER1 complex [cytosol] [Complex:R-HSA-196222] p-AXIN:CK1alpha:GSK3B:phospho-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] [Complex:R-HSA-3601577] p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] [Complex:R-HSA-195322] p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] [Complex:R-HSA-195297] p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] [Complex:R-HSA-195250] AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol]
(hasMember)	[CandidateSet:R-HSA-195284] CK1alpha (GSK3) [cytosol]
(output)	[Reaction:R-HSA-201685] Beta-catenin is released from the destruction complex
(physicalEntity)	[CatalystActivity:5610635] protein serine/threonine kinase activity of CSNK1A1 [cytosol]

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