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Schema
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Entries
Synthesis of bile acids and bile salts
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authored
[InstanceEdit:191331] Jassal, Bijay, 2007-01-19
created
[InstanceEdit:191989] Jassal, Bijay, 2007-01-26
dbId
192105
displayName
Synthesis of bile acids and bile salts
edited
[InstanceEdit:193475] D'Eustachio, P, 2007-02-17 19:40:28
eventOf
[Pathway:R-HSA-194068] Bile acid and bile salt metabolism - Homo sapiens
goBiologicalProcess
[GO_BiologicalProcess:20533] bile acid biosynthetic process
hasDiagram
false
hasEHLD
false
hasEvent
[Pathway:R-HSA-193368] Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol - Homo sapiens
[Pathway:R-HSA-193775] Synthesis of bile acids and bile salts via 24-hydroxycholesterol - Homo sapiens
[Pathway:R-HSA-193807] Synthesis of bile acids and bile salts via 27-hydroxycholesterol - Homo sapiens
[Reaction:R-HSA-191983] Cholesterol is hydroxylated to 25-hydroxycholesterol - Homo sapiens
[Reaction:R-HSA-192065] CYP7B1 7-hydroxylates 25OH-CHOL - Homo sapiens
[Reaction:R-HSA-8867667] OSBPs transport 25OH-CHOL from ER membrane to plasma membrane - Homo sapiens
[Reaction:R-HSA-8868402] OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane - Homo sapiens
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:192080] The enzymes, regulation, and genetics of bile acid synthesis
[LiteratureReference:193584] Cholesterol, hydroxycholesterols, and bile acids
modified
[InstanceEdit:10931649] Wright, Adam, 2024-03-08
name
Synthesis of bile acids and bile salts
orthologousEvent
[Pathway:R-PFA-192105] Synthesis of bile acids and bile salts - Plasmodium falciparum
[Pathway:R-SCE-192105] Synthesis of bile acids and bile salts - Saccharomyces cerevisiae
[Pathway:R-SPO-192105] Synthesis of bile acids and bile salts - Schizosaccharomyces pombe
[Pathway:R-DDI-192105] Synthesis of bile acids and bile salts - Dictyostelium discoideum
[Pathway:R-CEL-192105] Synthesis of bile acids and bile salts - Caenorhabditis elegans
[Pathway:R-DME-192105] Synthesis of bile acids and bile salts - Drosophila melanogaster
[Pathway:R-GGA-192105] Synthesis of bile acids and bile salts - Gallus gallus
[Pathway:R-XTR-192105] Synthesis of bile acids and bile salts - Xenopus tropicalis
[Pathway:R-DRE-192105] Synthesis of bile acids and bile salts - Danio rerio
[Pathway:R-SSC-192105] Synthesis of bile acids and bile salts - Sus scrofa
[Pathway:R-BTA-192105] Synthesis of bile acids and bile salts - Bos taurus
[Pathway:R-CFA-192105] Synthesis of bile acids and bile salts - Canis familiaris
[Pathway:R-RNO-192105] Synthesis of bile acids and bile salts - Rattus norvegicus
[Pathway:R-MMU-192105] Synthesis of bile acids and bile salts - Mus musculus
releaseDate
2007-05-15
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:197117] D'Eustachio, P, 2007-04-30 14:43:26
schemaClass
Pathway
species
[Species:48887] Homo sapiens
stId
R-HSA-192105
summation
[Summation:192000] In a healthy adult human, about 500 mg of cholesterol is con...
Referrals
(hasEvent)
[Pathway:R-HSA-194068] Bile acid and bile salt metabolism
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