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Reaction
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Entries
1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol
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authored
[InstanceEdit:1855226] Williams, MG, 2011-10-28
catalystActivity
[CatalystActivity:2024000] inositol heptakisphosphate kinase activity of IP6K1/3 [cytosol]
category
transition
compartment
[Compartment:70101] cytosol
created
[InstanceEdit:1855226] Williams, MG, 2011-10-28
crossReference
[DatabaseIdentifier:11880674] Rhea:37468
dbId
1855194
displayName
1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol
edited
[InstanceEdit:1855226] Williams, MG, 2011-10-28
eventOf
[Pathway:R-HSA-1855167] Synthesis of pyrophosphates in the cytosol - Homo sapiens
followingEvent
[Reaction:R-HSA-2023973] (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol - Homo sapiens
[Reaction:R-HSA-1855165] (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol - Homo sapiens
input
[SimpleEntity:R-ALL-1629740] 1-PP-IP5 [cytosol]
[SimpleEntity:R-ALL-113592] ATP [cytosol]
isChimeric
false
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:1889803] Identification and characterization of a novel inositol hexakisphosphate kinase
[LiteratureReference:1889868] A conserved family of enzymes that phosphorylate inositol hexakisphosphate
modified
[InstanceEdit:11879863] Wright, Adam, 2024-03-11
name
1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol
orthologousEvent
[Reaction:R-PFA-1855194] 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol - Plasmodium falciparum
[Reaction:R-DDI-1855194] 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol - Dictyostelium discoideum
[Reaction:R-DRE-1855194] 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol - Danio rerio
[Reaction:R-SCE-1855194] 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol - Saccharomyces cerevisiae
[Reaction:R-SPO-1855194] 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol - Schizosaccharomyces pombe
[Reaction:R-CEL-1855194] 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol - Caenorhabditis elegans
[Reaction:R-DME-1855194] 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol - Drosophila melanogaster
[Reaction:R-GGA-1855194] 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol - Gallus gallus
[Reaction:R-XTR-1855194] 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol - Xenopus tropicalis
[Reaction:R-SSC-1855194] 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol - Sus scrofa
[Reaction:R-BTA-1855194] 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol - Bos taurus
[Reaction:R-CFA-1855194] 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol - Canis familiaris
[Reaction:R-RNO-1855194] 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol - Rattus norvegicus
[Reaction:R-MMU-1855194] 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol - Mus musculus
output
[SimpleEntity:R-ALL-1629732] 1,5-(PP)2-IP4 [cytosol]
[SimpleEntity:R-ALL-29370] ADP [cytosol]
precedingEvent
[Reaction:R-HSA-1855216] IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol - Homo sapiens
[Reaction:R-HSA-2023973] (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol - Homo sapiens
releaseDate
2012-12-04
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:2562610] Wundenberg, Torsten, 2012-11-06
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-1855194
summation
[Summation:2023990] Inositol hexakisphosphate kinase 1 (IP6K1) and 3 (IP6K3) pho...
Referrals
(hasEvent)
[Pathway:R-HSA-1855167] Synthesis of pyrophosphates in the cytosol
(precedingEvent)
[Reaction:R-HSA-1855165] (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol
[Reaction:R-HSA-2023973] (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol
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