Reactome | Removal of the Flap Intermediate from the C-strand

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Removal of the Flap Intermediate from the C-strand Show undefined attributes

authored	[InstanceEdit:176728] Blackburn, EH, Seidel, J, 2006-03-09 19:41:08
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:174443] Gillespie, ME, 2006-02-17 20:47:42
dbId	174437
displayName	Removal of the Flap Intermediate from the C-strand
edited	[InstanceEdit:9686480] Orlic-Milacic, Marija, 2020-05-04
eventOf	[Pathway:R-HSA-174414] Processive synthesis on the C-strand of the telomere - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:263978] telomere maintenance via semi-conservative replication
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-174445] RPA binds to the Flap on the C-strand - Homo sapiens [Reaction:R-HSA-174451] Recruitment of DNA2 endonuclease to the C strand - Homo sapiens [Reaction:R-HSA-174441] Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand - Homo sapiens [Reaction:R-HSA-174446] Removal of remaining Flap from the C-strand - Homo sapiens
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:69057] Replication factors required for SV40 DNA replication in vitro. II. Switching of DNA polymerase alpha and delta during initiation of leading and lagging strand synthesis.
modified	[InstanceEdit:10871105] Wright, Adam, 2024-03-08
name	Removal of the Flap Intermediate from the C-strand
orthologousEvent	[Pathway:R-SPO-174437] Removal of the Flap Intermediate from the C-strand - Schizosaccharomyces pombe [Pathway:R-SSC-174437] Removal of the Flap Intermediate from the C-strand - Sus scrofa [Pathway:R-BTA-174437] Removal of the Flap Intermediate from the C-strand - Bos taurus [Pathway:R-CFA-174437] Removal of the Flap Intermediate from the C-strand - Canis familiaris [Pathway:R-RNO-174437] Removal of the Flap Intermediate from the C-strand - Rattus norvegicus [Pathway:R-MMU-174437] Removal of the Flap Intermediate from the C-strand - Mus musculus
precedingEvent	[Reaction:R-HSA-174438] Formation of the Flap Intermediate on the C-strand - Homo sapiens
releaseDate	2006-08-02
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:182786] Price, C, 2006-07-13 18:33:38 [InstanceEdit:9686481] Hayashi, Makoto T, 2020-04-29
revised	[InstanceEdit:425037] D'Eustachio, P, 2009-06-02 [InstanceEdit:9668944] Orlic-Milacic, Marija, 2019-12-02
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-174437
summation	[Summation:69167] Two endonucleases, Dna2 and flap endonuclease 1 (FEN-1), are...

Referrals

(hasEvent)

[Pathway:R-HSA-174414] Processive synthesis on the C-strand of the telomere