Reactome | Fusion of the influenza virion HA2 protein transmembrane domain to the host cell endosome membrane

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Fusion of the influenza virion HA2 protein transmembrane domain to the host cell endosome membrane Show undefined attributes

category	transition
compartment	[Compartment:24337] endocytic vesicle membrane [Compartment:171907] endosome lumen
created	[InstanceEdit:168327] 2007-04-16 22:35:07
dbId	168312
disease	[Disease:1660558] influenza
displayName	Fusion of the influenza virion HA2 protein transmembrane domain to the host cell endosome membrane
eventOf	[Pathway:R-HSA-168288] Fusion of the Influenza Virion to the Host Cell Endosome - Homo sapiens
followingEvent	[Reaction:R-HSA-168306] Concerted hemagglutinin pore formation - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:6589] fusion of virus membrane with host plasma membrane
input	[Complex:R-FLU-189182] Influenza A Viral Particle With A Fusion Competent HA2 [endosome lumen]
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:189373] Membrane fusion mechanisms: the influenza hemagglutinin paradigm and its implications for intracellular fusion
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Fusion of the influenza virion HA2 protein transmembrane domain to the host cell endosome membrane
output	[Complex:R-FLU-189138] Influenza A Viral Particle Docked At The Endocytic Vesicle Membrane [endocytic vesicle membrane]
precedingEvent	[Reaction:R-HSA-168324] Conformation change in hemagglutinin freeing the fusion peptide of HA2 - Homo sapiens
relatedSpecies	[Species:9031716] Influenza A virus
releaseDate	2006-01-23
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-168312
summation	[Summation:179374] The fusion peptide of its HA2 subunit interacts with the end...

Referrals

(hasEvent)	[Pathway:R-HSA-168288] Fusion of the Influenza Virion to the Host Cell Endosome
(precedingEvent)	[Reaction:R-HSA-168306] Concerted hemagglutinin pore formation

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