Reactome | NS1 Mediated Effects on Host Pathways

Schema > Pathway > Entries

authored	[InstanceEdit:5146782] Gillespie, ME, 2013-11-18
created	[InstanceEdit:168269] Gillespie, ME, 2005-11-14 17:18:07
dbId	168276
disease	[Disease:1660558] influenza
displayName	NS1 Mediated Effects on Host Pathways
edited	[InstanceEdit:5146790] Gillespie, ME, 2013-11-18
eventOf	[Pathway:R-HSA-168255] Influenza Infection - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:6550] modulation by virus of host cellular process
hasDiagram	false
hasEHLD	false
hasEvent	[BlackBoxEvent:R-HSA-1176059] Translocation of Influenza A virus nonstructural protein 1 (NS1A) into the nucleus - Homo sapiens [Reaction:R-HSA-6791035] Release of NS1 homodimer - Homo sapiens [Pathway:R-HSA-168315] Inhibition of Host mRNA Processing and RNA Silencing - Homo sapiens [Pathway:R-HSA-168305] Inhibition of Interferon Synthesis - Homo sapiens [Pathway:R-HSA-169131] Inhibition of PKR - Homo sapiens
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:195768] Orthomyxoviridae: The Viruses and Their Replication
modified	[InstanceEdit:9847082] Weiser, Joel, 2023-10-12
name	NS1 Mediated Effects on Host Pathways
relatedSpecies	[Species:9031716] Influenza A virus
releaseDate	2005-06-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:170177] Gale M, Jr, 2004-05-12 19:00:00
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-168276
summation	[Summation:169100] Viral NS1 protein is a nuclear, dimeric protein that is high...

(hasEvent)

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