Reactome | Formation of DSIF:NELF:HIV-1 early elongation complex

Schema > Reaction > Entries

Formation of DSIF:NELF:HIV-1 early elongation complex Show undefined attributes

authored	[InstanceEdit:165064] Matthews, L, Rice, AP, 2005-07-27 00:00:00
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:167073] Matthews, L, 2005-10-11 08:25:49
dbId	167085
disease	[Disease:1660559] Human immunodeficiency virus infectious disease
displayName	Formation of DSIF:NELF:HIV-1 early elongation complex
edited	[InstanceEdit:165066] Matthews, L, 2005-07-26 23:29:22
eventOf	[Pathway:R-HSA-167158] Formation of the HIV-1 Early Elongation Complex - Homo sapiens
followingEvent	[Reaction:R-HSA-167087] Limited elongation of the HIV-1 transcript - Homo sapiens [Reaction:R-HSA-167478] Abortive termination of HIV-1 early transcription elongation by DSIF:NELF - Homo sapiens [Reaction:R-HSA-167084] Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex - Homo sapiens
inferredFrom	[Reaction:R-HSA-113402] Formation of DSIF:NELF:early elongation complex - Homo sapiens
input	[Complex:R-HSA-112432] NELF complex [nucleoplasm] [SimpleEntity:R-ALL-9757634] NTP [nucleoplasm] [Complex:R-HSA-167070] RNA Pol II (hypophosphorylated) complex bound to DSIF protein [nucleoplasm]
isInDisease	true
isInferred	true
literatureReference	[LiteratureReference:170758] NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Formation of DSIF:NELF:HIV-1 early elongation complex
output	[Complex:R-HSA-167078] DSIF:NELF:early elongation complex [nucleoplasm] [SimpleEntity:R-ALL-9757634] NTP [nucleoplasm]
precedingEvent	[Reaction:R-HSA-112437] Formation of NELF complex - Homo sapiens [Reaction:R-HSA-167083] DSIF complex binds to RNA Pol II (hypophosphorylated) - Homo sapiens
relatedSpecies	[Species:164493] Human immunodeficiency virus 1
releaseDate	2005-06-13
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-167085
summation	[Summation:170748] This HIV-1 event was inferred from the corresponding human R...

Referrals

(precedingEvent)	[Reaction:R-HSA-167087] Limited elongation of the HIV-1 transcript [Reaction:R-HSA-167478] Abortive termination of HIV-1 early transcription elongation by DSIF:NELF [Reaction:R-HSA-167084] Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex
(hasEvent)	[Pathway:R-HSA-167158] Formation of the HIV-1 Early Elongation Complex
(inferredTo)	[Reaction:R-HSA-113402] Formation of DSIF:NELF:early elongation complex