Reactome | HEXB(316-556) [lysosomal lumen]

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HEXB(316-556) [lysosomal lumen] Show undefined attributes

compartment	[Compartment:161320] lysosomal lumen
componentOf	[Complex:R-HSA-9842389] Mature HEXB [lysosomal lumen] - Homo sapiens
created	[InstanceEdit:1605804] Jassal, Bijay, 2011-09-21
dbId	1605605
displayName	HEXB(316-556) [lysosomal lumen]
endCoordinate	556
hasModifiedResidue	[InterChainCrosslinkedResidue:9842373] Inter-chain Crosslink via L-cystine (cross-link) at 360 and 309
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-1605605] Hexb [lysosomal lumen] - Mus musculus [EntityWithAccessionedSequence:R-RNO-1605605] Hexb [lysosomal lumen] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-1605605] HEXB [lysosomal lumen] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-1605605] HEXB [lysosomal lumen] - Bos taurus [EntityWithAccessionedSequence:R-SSC-1605605] HEXB [lysosomal lumen] - Sus scrofa [EntityWithAccessionedSequence:R-XTR-1605605] hexb [lysosomal lumen] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-1605605] HEXB [lysosomal lumen] - Gallus gallus [EntityWithAccessionedSequence:R-DME-1605605] Hexo1 [lysosomal lumen] - Drosophila melanogaster [EntityWithAccessionedSequence:R-DME-1605605-2] fdl [lysosomal lumen] - Drosophila melanogaster [EntityWithAccessionedSequence:R-DME-1605605-3] Hexo2 [lysosomal lumen] - Drosophila melanogaster [DefinedSet:R-DME-1605605-4] Homologues of HEXB(316-556) [lysosomal lumen] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-1605605] hex-1 [lysosomal lumen] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-DDI-1605605] hexb2 [lysosomal lumen] - Dictyostelium discoideum
literatureReference	[LiteratureReference:1660671] Crystal structure of human beta-hexosaminidase B: understanding the molecular basis of Sandhoff and Tay-Sachs disease
modified	[InstanceEdit:9842382] Stephan, Ralf, 2023-08-27
name	HEXB(316-556) HEXBA Beta-hexosaminidase subunit beta A HEXB_HUMAN HEXB
referenceEntity	[ReferenceGeneProduct:56474] UniProt:P07686 HEXB
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-1605605
startCoordinate	316

Referrals

(hasComponent)

[Complex:R-HSA-9842389] Mature HEXB [lysosomal lumen]

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