Reactome | Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine

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Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine Show undefined attributes

authored	[InstanceEdit:159408] Jassal, B, 2005-03-09 13:42:30
catalystActivity	[CatalystActivity:159410] acyltransferase activity of BAAT [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:159408] Jassal, B, 2005-03-09 13:42:30
dbId	159431
displayName	Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine
edited	[InstanceEdit:194157] D'Eustachio, P, 2007-03-09 21:29:31
eventOf	[Pathway:R-HSA-159418] Recycling of bile acids and salts - Homo sapiens
followingEvent	[Reaction:R-HSA-193362] ABCB11 transports bile salts from cytosol to extracellular region - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:12647] bile acid metabolic process
input	[DefinedSet:R-ALL-194073] choloyl-CoA; chenodeoxycholoyl-CoA [cytosol] [DefinedSet:R-ALL-194069] Gly, TAU [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:159413] Glycine and taurine conjugation of bile acids by a single enzyme. Molecular cloning and expression of human liver bile acid CoA:amino acid N-acyltransferase. [LiteratureReference:159400] Purification and characterization of bile acid-CoA:amino acid N-acyltransferase from human liver [LiteratureReference:193480] Subcellular organization of bile acid amidation in human liver: a key issue in regulating the biosynthesis of bile salts
modified	[InstanceEdit:10740525] Wright, Adam, 2024-03-08
name	Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine
orthologousEvent	[Reaction:R-CEL-159431] Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine - Caenorhabditis elegans [Reaction:R-GGA-159431] Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine - Gallus gallus [Reaction:R-XTR-159431] Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine - Xenopus tropicalis [Reaction:R-SSC-159431] Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine - Sus scrofa [Reaction:R-CFA-159431] Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine - Canis familiaris [Reaction:R-RNO-159431] Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine - Rattus norvegicus [Reaction:R-MMU-159431] Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine - Mus musculus
output	[DefinedSet:R-ALL-193416] bile salts [cytosol] [SimpleEntity:R-ALL-76194] CoA-SH [cytosol]
precedingEvent	[Reaction:R-HSA-159425] Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) - Homo sapiens
releaseDate	2007-05-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:197117] D'Eustachio, P, 2007-04-30 14:43:26
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-159431
summation	[Summation:194085] Cytosolic bile acid-CoA conjugates (choloyl-CoA; chenodeoxyc...

Referrals

(precedingEvent)	[Reaction:R-HSA-193362] ABCB11 transports bile salts from cytosol to extracellular region
(hasEvent)	[Pathway:R-HSA-159418] Recycling of bile acids and salts