Reactome | Glucuronidation

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Glucuronidation Show undefined attributes

authored	[InstanceEdit:156583] Jassal, B, 2004-11-29 11:42:34
created	[InstanceEdit:156583] Jassal, B, 2004-11-29 11:42:34
dbId	156588
displayName	Glucuronidation
edited	[InstanceEdit:350358] Jassal, Bijay, 2008-05-19
eventOf	[Pathway:R-HSA-156580] Phase II - Conjugation of compounds - Homo sapiens
figure	[Figure:158026] /figures/UDPGA_formation.jpg
goBiologicalProcess	[GO_BiologicalProcess:2132929] cellular glucuronidation
hasDiagram	false
hasEHLD	false
hasEvent	[Pathway:R-HSA-173599] Formation of the active cofactor, UDP-glucuronate - Homo sapiens [Reaction:R-HSA-174931] UGTs transfer GlcA from UDP-GlcA to O-centre substrates - Homo sapiens [Reaction:R-HSA-9632039] UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG - Homo sapiens [Reaction:R-HSA-159194] UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG - Homo sapiens [Reaction:R-HSA-9632038] UGT1A1 tetramer transfers GlcA from UDP-GlcA to BMG to form BDG - Homo sapiens [Reaction:R-HSA-159179] UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG - Homo sapiens [Reaction:R-HSA-8941701] UGT1A10 transfers GlcA from UDP-GlcA to GCTN - Homo sapiens [Reaction:R-HSA-174916] Formation of N-glucuronides - Homo sapiens [Reaction:R-HSA-5694563] ABHD10 hydrolyses MPAG - Homo sapiens
isInDisease	false
isInferred	false
literatureReference	[Book:76380] 9780071470513 Parkinson, A Casarett and Doull's Toxicology 5th Edn [LiteratureReference:159155] Human UDP-glucuronosyltransferases: metabolism, expression, and disease [LiteratureReference:266234] Glucuronidation and the UDP-glucuronosyltransferases in health and disease
modified	[InstanceEdit:10901498] Wright, Adam, 2024-03-08
name	Glucuronidation
orthologousEvent	[Pathway:R-SCE-156588] Glucuronidation - Saccharomyces cerevisiae [Pathway:R-SPO-156588] Glucuronidation - Schizosaccharomyces pombe [Pathway:R-DDI-156588] Glucuronidation - Dictyostelium discoideum [Pathway:R-CEL-156588] Glucuronidation - Caenorhabditis elegans [Pathway:R-DME-156588] Glucuronidation - Drosophila melanogaster [Pathway:R-GGA-156588] Glucuronidation - Gallus gallus [Pathway:R-XTR-156588] Glucuronidation - Xenopus tropicalis [Pathway:R-DRE-156588] Glucuronidation - Danio rerio [Pathway:R-SSC-156588] Glucuronidation - Sus scrofa [Pathway:R-BTA-156588] Glucuronidation - Bos taurus [Pathway:R-CFA-156588] Glucuronidation - Canis familiaris [Pathway:R-RNO-156588] Glucuronidation - Rattus norvegicus [Pathway:R-MMU-156588] Glucuronidation - Mus musculus
releaseDate	2008-06-30
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-156588
summation	[Summation:156591] Glucuronidation conjugation utilizes UDP-glucuronosyltransfe...

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[Pathway:R-HSA-156580] Phase II - Conjugation of compounds

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