Reactome | PTPMT1 dephosphorylates PGP to PG

Schema > Reaction > Entries

PTPMT1 dephosphorylates PGP to PG Show undefined attributes

authored	[InstanceEdit:1602345] Williams, MG, 2011-09-14
catalystActivity	[CatalystActivity:3446787] phosphatidylglycerophosphatase activity of PTPMT1 [mitochondrial inner membrane]
category	transition
compartment	[Compartment:70616] mitochondrial inner membrane [Compartment:5460] mitochondrial matrix
created	[InstanceEdit:1483214] Williams, MG, 2011-08-12
crossReference	[DatabaseIdentifier:11879954] Rhea:33751
dbId	1483197
displayName	PTPMT1 dephosphorylates PGP to PG
edited	[InstanceEdit:1482514] Williams, MG, 2011-08-12
eventOf	[Pathway:R-HSA-1483148] Synthesis of PG - Homo sapiens
followingEvent	[Reaction:R-HSA-1482847] PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) - Homo sapiens [Reaction:R-HSA-1482745] PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) - Homo sapiens [Reaction:R-HSA-1483063] PG and CDP-DAG are converted to CL by CRLS1 - Homo sapiens
inferredFrom	[Reaction:R-MMU-3446785] Ptpmt1 dephosphorylates PGP to PG - Mus musculus
input	[SimpleEntity:R-ALL-113521] H2O [mitochondrial matrix] [SimpleEntity:R-ALL-1524059] PGP [mitochondrial inner membrane]
isChimeric	false
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:3446788] Mitochondrial phosphatase PTPMT1 is essential for cardiolipin biosynthesis
modified	[InstanceEdit:11879863] Wright, Adam, 2024-03-11
name	PTPMT1 dephosphorylates PGP to PG
output	[SimpleEntity:R-ALL-1524042] PG [mitochondrial inner membrane] [SimpleEntity:R-ALL-113548] Pi [mitochondrial matrix]
precedingEvent	[Reaction:R-HSA-1482939] CDP-DAG is converted to PGP by PGS1 - Homo sapiens
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:3451012] Jassal, Bijay, 2013-05-16
revised	[InstanceEdit:3446786] D'Eustachio, P, 2013-05-15
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1483197
summation	[Summation:1482960] At the inner mitochondrial (IM) membrane, PTPMT1 (phosphatid...

Referrals

(precedingEvent)	[Reaction:R-HSA-1482847] PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) [Reaction:R-HSA-1482745] PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) [Reaction:R-HSA-1483063] PG and CDP-DAG are converted to CL by CRLS1
(hasEvent)	[Pathway:R-HSA-1483148] Synthesis of PG
(inferredTo)	[Reaction:R-MMU-3446785] Ptpmt1 dephosphorylates PGP to PG