Reactome | PC is transphosphatidylated to PG by PLD1-4/6

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PC is transphosphatidylated to PG by PLD1-4/6 Show undefined attributes

authored	[InstanceEdit:1602345] Williams, MG, 2011-09-14
catalystActivity	[CatalystActivity:1524118] phospholipase D activity of PLD1-4/6 [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:1483214] Williams, MG, 2011-08-12
dbId	1483142
displayName	PC is transphosphatidylated to PG by PLD1-4/6
edited	[InstanceEdit:1482514] Williams, MG, 2011-08-12
eventOf	[Pathway:R-HSA-1483148] Synthesis of PG - Homo sapiens
followingEvent	[Reaction:R-HSA-1482907] PG is hydrolyzed to 1-acyl LPG by PLA2G2A - Homo sapiens [Reaction:R-HSA-1482920] PG is hydrolyzed to 2-acyl LPG by PLA2[14] - Homo sapiens [Reaction:R-HSA-1482900] PG is hydrolyzed to 1-acyl LPG by PLA2[1] - Homo sapiens [Reaction:R-HSA-1483218] PG transports from the ER membrane to the late endosome membrane - Homo sapiens
inferredFrom	[Reaction:R-MMU-1483172] PC is transphosphatidylated to PG by Pld1-4/6 - Mus musculus
input	[SimpleEntity:R-ALL-76116] Glycerol [cytosol] [SimpleEntity:R-ALL-426925] PC [endoplasmic reticulum membrane]
isChimeric	false
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:1483192] Human ADP-ribosylation factor-activated phosphatidylcholine-specific phospholipase D defines a new and highly conserved gene family [LiteratureReference:1602044] Characterization of human PLD2 and the analysis of PLD isoform splice variants [LiteratureReference:1602052] A human homolog of the vaccinia virus HindIII K4L gene is a member of the phospholipase D superfamily
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	PC is transphosphatidylated to PG by PLD1-4/6
output	[SimpleEntity:R-ALL-264618] Cho [cytosol] [SimpleEntity:R-ALL-1483256] PG [endoplasmic reticulum membrane]
precedingEvent	[Reaction:R-HSA-1483219] PC is exchanged with PI by PITPNB - Homo sapiens [Reaction:R-HSA-1482961] CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane - Homo sapiens [Reaction:R-HSA-1482547] 1-acyl LPC is acylated to PC by LPCAT - Homo sapiens [Reaction:R-HSA-1482533] 2-acyl LPC is acylated to PC by LPCAT - Homo sapiens
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1483142
summation	[Summation:1483073] In the endoplasmic reticulum (ER) membrane, phospholipase D1...

Referrals

(hasEvent)	[Pathway:R-HSA-1483148] Synthesis of PG
(precedingEvent)	[Reaction:R-HSA-1482907] PG is hydrolyzed to 1-acyl LPG by PLA2G2A [Reaction:R-HSA-1482920] PG is hydrolyzed to 2-acyl LPG by PLA2[14] [Reaction:R-HSA-1482900] PG is hydrolyzed to 1-acyl LPG by PLA2[1] [Reaction:R-HSA-1483218] PG transports from the ER membrane to the late endosome membrane
(inferredTo)	[Reaction:R-MMU-1483172] PC is transphosphatidylated to PG by Pld1-4/6