Reactome | 1-acyl LPG is acylated to PG by LPGAT

Schema > Reaction > Entries

1-acyl LPG is acylated to PG by LPGAT Show undefined attributes

authored	[InstanceEdit:1602345] Williams, MG, 2011-09-14
catalystActivity	[CatalystActivity:1524031] 1-acylglycerol-3-phosphate O-acyltransferase activity of LPGAT [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:1482525] Williams, MG, 2011-08-12
dbId	1482539
displayName	1-acyl LPG is acylated to PG by LPGAT
edited	[InstanceEdit:1482514] Williams, MG, 2011-08-12
eventOf	[Pathway:R-HSA-1482925] Acyl chain remodelling of PG - Homo sapiens
followingEvent	[Reaction:R-HSA-1482900] PG is hydrolyzed to 1-acyl LPG by PLA2[1] - Homo sapiens [Reaction:R-HSA-1483218] PG transports from the ER membrane to the late endosome membrane - Homo sapiens [Reaction:R-HSA-1482907] PG is hydrolyzed to 1-acyl LPG by PLA2G2A - Homo sapiens [Reaction:R-HSA-1482920] PG is hydrolyzed to 2-acyl LPG by PLA2[14] - Homo sapiens
input	[SimpleEntity:R-ALL-1498740] 1-acyl LPG [endoplasmic reticulum membrane] [SimpleEntity:R-ALL-1500578] acyl-CoA [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1482687] Molecular identification of a novel mammalian brain isoform of acyl-CoA:lysophospholipid acyltransferase with prominent ethanolamine lysophospholipid acylating activity, LPEAT2 [LiteratureReference:1482553] Cloning and characterization a novel human 1-acyl-sn-glycerol-3-phosphate acyltransferase gene AGPAT7 [LiteratureReference:1482617] Identification and characterization of a gene encoding human LPGAT1, an endoplasmic reticulum-associated lysophosphatidylglycerol acyltransferase [LiteratureReference:1482541] Cloning and characterization of mouse lung-type acyl-CoA:lysophosphatidylcholine acyltransferase 1 (LPCAT1). Expression in alveolar type II cells and possible involvement in surfactant production [LiteratureReference:1482640] Identification and characterization of a lysophosphatidylcholine acyltransferase in alveolar type II cells
modified	[InstanceEdit:10931649] Wright, Adam, 2024-03-08
name	1-acyl LPG is acylated to PG by LPGAT
orthologousEvent	[Reaction:R-PFA-1482539] 1-acyl LPG is acylated to PG by LPGAT - Plasmodium falciparum [Reaction:R-DDI-1482539] 1-acyl LPG is acylated to PG by LPGAT - Dictyostelium discoideum [Reaction:R-DRE-1482539] 1-acyl LPG is acylated to PG by LPGAT - Danio rerio [Reaction:R-SCE-1482539] 1-acyl LPG is acylated to PG by LPGAT - Saccharomyces cerevisiae [Reaction:R-SPO-1482539] 1-acyl LPG is acylated to PG by LPGAT - Schizosaccharomyces pombe [Reaction:R-CFA-1482539] 1-acyl LPG is acylated to PG by LPGAT - Canis familiaris [Reaction:R-MMU-1482539] 1-acyl LPG is acylated to PG by LPGAT - Mus musculus [Reaction:R-CEL-1482539] 1-acyl LPG is acylated to PG by LPGAT - Caenorhabditis elegans [Reaction:R-DME-1482539] 1-acyl LPG is acylated to PG by LPGAT - Drosophila melanogaster [Reaction:R-GGA-1482539] 1-acyl LPG is acylated to PG by LPGAT - Gallus gallus [Reaction:R-XTR-1482539] 1-acyl LPG is acylated to PG by LPGAT - Xenopus tropicalis [Reaction:R-SSC-1482539] 1-acyl LPG is acylated to PG by LPGAT - Sus scrofa [Reaction:R-BTA-1482539] 1-acyl LPG is acylated to PG by LPGAT - Bos taurus [Reaction:R-RNO-1482539] 1-acyl LPG is acylated to PG by LPGAT - Rattus norvegicus
output	[SimpleEntity:R-ALL-76194] CoA-SH [cytosol] [SimpleEntity:R-ALL-1483256] PG [endoplasmic reticulum membrane]
precedingEvent	[Reaction:R-HSA-1482900] PG is hydrolyzed to 1-acyl LPG by PLA2[1] - Homo sapiens [Reaction:R-HSA-1482907] PG is hydrolyzed to 1-acyl LPG by PLA2G2A - Homo sapiens
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1482539
summation	[Summation:1482552] At the endoplasmic reticulum (ER) membrane, lysophospholipid...

Referrals

(hasEvent)	[Pathway:R-HSA-1482925] Acyl chain remodelling of PG
(precedingEvent)	[Reaction:R-HSA-1483218] PG transports from the ER membrane to the late endosome membrane [Reaction:R-HSA-1482907] PG is hydrolyzed to 1-acyl LPG by PLA2G2A [Reaction:R-HSA-1482920] PG is hydrolyzed to 2-acyl LPG by PLA2[14] [Reaction:R-HSA-1482900] PG is hydrolyzed to 1-acyl LPG by PLA2[1]

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