Reactome | ESR1 dimer:ESTG [nucleoplasm]

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ESR1 dimer:ESTG [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-9011919] KDM4B gene:nucleoplasm:ESR1:ESTG [nucleoplasm] - Homo sapiens [Complex:R-HSA-9023841] CTSD gene:ESR1:ESTG [nucleoplasm] - Homo sapiens [Complex:R-HSA-9011932] BLC2 gene:HIST1H2AC nucleosome:ESR1:ESTG:EP300 [nucleoplasm] - Homo sapiens [Complex:R-HSA-9018491] FOXA1:GATA3:ESR1:ESTG:EP300 [nucleoplasm] - Homo sapiens
consumedByEvent	[BlackBoxEvent:R-HSA-9038161] Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG - Homo sapiens [Reaction:R-HSA-9018325] ESR1:ESTG binds CXXC5 gene - Homo sapiens [Reaction:R-HSA-8939904] Activated ESR1 binds the RUNX2 gene promoter - Homo sapiens [Reaction:R-HSA-8932070] ESR1 binds the AXIN1 gene - Homo sapiens [Reaction:R-HSA-9038052] GREB1 binds ESR1:ESTG and co-activators - Homo sapiens [Reaction:R-HSA-9023845] ESR1:ESTG binds to proximal and distal regions of the CTSD promoter - Homo sapiens [Reaction:R-HSA-9011952] ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers - Homo sapiens [Reaction:R-HSA-9011997] ESR1:ESTG, JUND:FOSB and Cohesin Complex bind distal enhancer elements in MYC gene promoter - Homo sapiens [Reaction:R-HSA-8931981] RUNX1 binds ESR1 - Homo sapiens [Reaction:R-HSA-1254386] ERBB4s80 forms a complex with estrogen receptor ESR1 - Homo sapiens [Reaction:R-HSA-9018503] ESR1:ESTG bind the EBAG9 5' region - Homo sapiens [Reaction:R-HSA-9011983] Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes - Homo sapiens [Reaction:R-HSA-9018499] ESR1:ESTG and EP300 are recruited to TFF3 promoter - Homo sapiens
created	[InstanceEdit:1254385] Orlic-Milacic, Marija, 2011-04-29
dbId	1254381
displayName	ESR1 dimer:ESTG [nucleoplasm]
hasComponent	[Complex:R-HSA-1254384] ESR1 homodimer [nucleoplasm] 2 × [SimpleEntity:R-ALL-1254400] ESTG [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-1254381] ESR1 dimer:ESTG [nucleoplasm] - Mus musculus [Complex:R-RNO-1254381] ESR1 dimer:ESTG [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-1254381] ESR1 dimer:ESTG [nucleoplasm] - Canis familiaris [Complex:R-BTA-1254381] ESR1 dimer:ESTG [nucleoplasm] - Bos taurus [Complex:R-SSC-1254381] ESR1 dimer:ESTG [nucleoplasm] - Sus scrofa [Complex:R-DRE-1254381] ESR1 dimer:ESTG [nucleoplasm] - Danio rerio [Complex:R-XTR-1254381] ESR1 dimer:ESTG [nucleoplasm] - Xenopus tropicalis [Complex:R-GGA-1254381] ESR1 dimer:ESTG [nucleoplasm] - Gallus gallus [Complex:R-DME-1254381] ESR1 dimer:ESTG [nucleoplasm] - Drosophila melanogaster [Complex:R-CEL-1254381] ESR1 dimer:ESTG [nucleoplasm] - Caenorhabditis elegans [Complex:R-DDI-1254381] ESR1 dimer:ESTG [nucleoplasm] - Dictyostelium discoideum [Complex:R-SPO-1254381] ESR1 dimer:ESTG [nucleoplasm] - Schizosaccharomyces pombe [Complex:R-SCE-1254381] ESR1 dimer:ESTG [nucleoplasm] - Saccharomyces cerevisiae [Complex:R-PFA-1254381] ESR1 dimer:ESTG [nucleoplasm] - Plasmodium falciparum
isChimeric	false
memberOf	[DefinedSet:R-HSA-9710004] ESR multimer:ESTG [nucleoplasm] - Homo sapiens
modified	[InstanceEdit:9710005] Jassal, Bijay, 2020-12-21
name	ESR1 dimer:ESTG
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-1254381

Referrals

(hasComponent)	[Complex:R-HSA-9011919] KDM4B gene:nucleoplasm:ESR1:ESTG [nucleoplasm] [Complex:R-HSA-9038050] GREB1:ESR1:ESTG:EP300:CREBBP [nucleoplasm] [Complex:R-HSA-9011932] BLC2 gene:HIST1H2AC nucleosome:ESR1:ESTG:EP300 [nucleoplasm] [Complex:R-HSA-9023841] CTSD gene:ESR1:ESTG [nucleoplasm] [Complex:R-HSA-9038156] ESR1:ER:PGR:P4 [nucleoplasm] [Complex:R-HSA-9018328] CXXC5 gene:ESR1:ESTG [nucleoplasm] [Complex:R-HSA-9011911] KDM4B-regulated genes:nucleosome:ESR1:ESTG [nucleoplasm] [Complex:R-HSA-9011913] KDM4B-regulated genes:H3K9me3 nucleosome:ESR1:ESTG:KDM4B [nucleoplasm] [Complex:R-HSA-9011925] GREB1 gene:nucleosome:ESR1:ESTG [nucleoplasm] [Complex:R-HSA-9011929] CCND1 gene:nucleosome:ESR1:ESTG [nucleoplasm] [Complex:R-HSA-9009370] ESTG:ESR1 dimer:ATF2:JUN [nucleoplasm] [Complex:R-HSA-9009373] ESTG:ESR1 dimer:JUN:FOS [nucleoplasm] [Complex:R-HSA-8939910] ESR1:estrogen:RUNX2 gene [nucleoplasm] [Complex:R-HSA-8932051] ESR1:estrogen:AXIN1 gene [nucleoplasm] [Complex:R-HSA-8931986] RUNX1:CBFB:ESR1:estrogen [nucleoplasm] [Complex:R-HSA-1254397] ERBB4s80:ESR1:estrogen [nucleoplasm] [Complex:R-HSA-9018506] EBAG9 gene:ESR1:ESTG [nucleoplasm] [Complex:R-HSA-9011896] MYC gene, BCL2 gene:HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] [Complex:R-HSA-9011891] MYC gene, BLC2 gene:H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] [Complex:R-HSA-9018491] FOXA1:GATA3:ESR1:ESTG:EP300 [nucleoplasm] [Complex:R-HSA-9018479] TFF3 gene:FOXA1:GATA3:ESR1:ESTG:EP300 [nucleoplasm] [Complex:R-HSA-9012291] ESR1:ESTG:P-TEFb [nucleoplasm] [Complex:R-HSA-9011887] MYC gene:ESR1:ESTG:JUND:FOSB:Cohesin Complex [nucleoplasm] [Complex:R-HSA-9011878] MYC gene:nucleoplasm:ESR1:ESTG [nucleoplasm] [Complex:R-HSA-9011883] MYC gene:HIST1H2AC nucleosome:ESR1:ESTG:EP300:NCOA3 [nucleoplasm]
(input)	[Reaction:R-HSA-9038052] GREB1 binds ESR1:ESTG and co-activators [Reaction:R-HSA-9023845] ESR1:ESTG binds to proximal and distal regions of the CTSD promoter [BlackBoxEvent:R-HSA-9038161] Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG [Reaction:R-HSA-9018325] ESR1:ESTG binds CXXC5 gene [Reaction:R-HSA-9011952] ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers [Reaction:R-HSA-9011997] ESR1:ESTG, JUND:FOSB and Cohesin Complex bind distal enhancer elements in MYC gene promoter [Reaction:R-HSA-8939904] Activated ESR1 binds the RUNX2 gene promoter [Reaction:R-HSA-8932070] ESR1 binds the AXIN1 gene [Reaction:R-HSA-8931981] RUNX1 binds ESR1 [Reaction:R-HSA-1254386] ERBB4s80 forms a complex with estrogen receptor ESR1 [Reaction:R-HSA-9018503] ESR1:ESTG bind the EBAG9 5' region [Reaction:R-HSA-9011983] Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes [Reaction:R-HSA-9018499] ESR1:ESTG and EP300 are recruited to TFF3 promoter
(hasMember)	[DefinedSet:R-HSA-9710004] ESR multimer:ESTG [nucleoplasm]
(activeUnit)	[PositiveGeneExpressionRegulation:R-HSA-9011965] Positive gene expression regulation by 'KDM4B gene:nucleoplasm:ESR1:ESTG [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-9011951] Positive gene expression regulation by 'GREB1 gene:nucleosome:ESR1:ESTG:ZNF217:NCOA3:NR5A2 [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-9011946] Positive gene expression regulation by 'CCND1 gene:nucleosome:ESR1:ESTG [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-8939947] Positive gene expression regulation by 'ESR1:estrogen:RUNX2 gene [nucleoplasm]' [NegativeGeneExpressionRegulation:R-HSA-8932074] Negative gene expression regulation by 'ESR1:estrogen:AXIN1 gene [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-9018527] Positive gene expression regulation by 'EBAG9 gene:ESR1:ESTG [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-9011977] Positive gene expression regulation by 'MYC gene:ESR1:ESTG:JUND:FOSB:Cohesin Complex [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-9011994] Positive gene expression regulation by 'MYC gene:nucleoplasm:ESR1:ESTG [nucleoplasm]'

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