Reactome | RHAG transports CO2 from extracellular region to cytosol

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RHAG transports CO2 from extracellular region to cytosol Show undefined attributes

authored	[InstanceEdit:1237008] May, B, 2011-03-24
catalystActivity	[CatalystActivity:1237071] carbon dioxide transmembrane transporter activity of RHAG [plasma membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:1237041] May, B, 2011-03-30
crossReference	[DatabaseIdentifier:11880324] Rhea:74891
dbId	1237069
displayName	RHAG transports CO2 from extracellular region to cytosol
edited	[InstanceEdit:1237008] May, B, 2011-03-24
eventOf	[Pathway:R-HSA-1237044] Erythrocytes take up carbon dioxide and release oxygen - Homo sapiens
followingEvent	[Reaction:R-HSA-1237325] Hemoglobin A is protonated and carbamated causing release of oxygen - Homo sapiens [Reaction:R-HSA-1475435] CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- - Homo sapiens
input	[SimpleEntity:R-ALL-1237009] CO2 [extracellular region]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1236995] RhAG protein of the Rhesus complex is a CO2 channel in the human red cell membrane [LiteratureReference:1236991] Relative CO2/NH3 selectivities of AQP1, AQP4, AQP5, AmtB, and RhAG [LiteratureReference:1237207] Red cell membrane CO2 permeability in normal human blood and in blood deficient in various blood groups, and effect of DIDS
modified	[InstanceEdit:11879863] Wright, Adam, 2024-03-11
name	RHAG transports CO2 from extracellular region to cytosol RhAG passively translocates carbon dioxide from the extracellular region to the cytosol
orthologousEvent	[Reaction:R-DDI-1237069] RHAG transports CO2 from extracellular region to cytosol - Dictyostelium discoideum [Reaction:R-CEL-1237069] RHAG transports CO2 from extracellular region to cytosol - Caenorhabditis elegans [Reaction:R-DME-1237069] RHAG transports CO2 from extracellular region to cytosol - Drosophila melanogaster [Reaction:R-GGA-1237069] RHAG transports CO2 from extracellular region to cytosol - Gallus gallus [Reaction:R-XTR-1237069] RHAG transports CO2 from extracellular region to cytosol - Xenopus tropicalis [Reaction:R-DRE-1237069] RHAG transports CO2 from extracellular region to cytosol - Danio rerio [Reaction:R-SSC-1237069] RHAG transports CO2 from extracellular region to cytosol - Sus scrofa [Reaction:R-BTA-1237069] RHAG transports CO2 from extracellular region to cytosol - Bos taurus [Reaction:R-CFA-1237069] RHAG transports CO2 from extracellular region to cytosol - Canis familiaris [Reaction:R-RNO-1237069] RHAG transports CO2 from extracellular region to cytosol - Rattus norvegicus [Reaction:R-MMU-1237069] RHAG transports CO2 from extracellular region to cytosol - Mus musculus
output	[SimpleEntity:R-ALL-113528] CO2 [cytosol]
precedingEvent	[Reaction:R-HSA-70967] IDH3 complex decarboxylates isocitrate - Homo sapiens [Reaction:R-HSA-450984] IDH2 dimer decarboxylates isocitrate - Homo sapiens [Reaction:R-HSA-71401] OGDH dimer decarboxylates 2-OG - Homo sapiens
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2207684] Jassal, B, 2012-04-27
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1237069
summation	[Summation:1244337] The Rhesus blood group type A glycoprotein (RhAG) passively ...

Referrals

(hasEvent)	[Pathway:R-HSA-1237044] Erythrocytes take up carbon dioxide and release oxygen
(precedingEvent)	[Reaction:R-HSA-1237325] Hemoglobin A is protonated and carbamated causing release of oxygen [Reaction:R-HSA-1475435] CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3-
(reverseReaction)	[Reaction:R-HSA-1247645] RHAG transports CO2 from cytosol to extracellular region