Reactome | AQP1 tetramer transports CO2 from extracellular region to cytosol

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AQP1 tetramer transports CO2 from extracellular region to cytosol Show undefined attributes

authored	[InstanceEdit:1237008] May, B, 2011-03-24
catalystActivity	[CatalystActivity:1237058] carbon dioxide transmembrane transporter activity of AQP1 tetramer [plasma membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:1237041] May, B, 2011-03-30
crossReference	[DatabaseIdentifier:11880323] Rhea:74891
dbId	1237042
displayName	AQP1 tetramer transports CO2 from extracellular region to cytosol
edited	[InstanceEdit:1237008] May, B, 2011-03-24
eventOf	[Pathway:R-HSA-1237044] Erythrocytes take up carbon dioxide and release oxygen - Homo sapiens
followingEvent	[Reaction:R-HSA-1475435] CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- - Homo sapiens [Reaction:R-HSA-1237325] Hemoglobin A is protonated and carbamated causing release of oxygen - Homo sapiens
input	[SimpleEntity:R-ALL-1237009] CO2 [extracellular region]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1237002] Aquaporin-1 and HCO3(-)-Cl- transporter-mediated transport of CO2 across the human erythrocyte membrane [LiteratureReference:1236991] Relative CO2/NH3 selectivities of AQP1, AQP4, AQP5, AmtB, and RhAG [LiteratureReference:1237207] Red cell membrane CO2 permeability in normal human blood and in blood deficient in various blood groups, and effect of DIDS [LiteratureReference:1237220] Evidence that aquaporin 1 is a major pathway for CO2 transport across the human erythrocyte membrane [LiteratureReference:1237270] Effect of expressing the water channel aquaporin-1 on the CO2 permeability of Xenopus oocytes
modified	[InstanceEdit:11879863] Wright, Adam, 2024-03-11
name	AQP1 tetramer transports CO2 from extracellular region to cytosol AQP1 passively tranlocates carbon dioxide from the extracellular region to the cytosol
orthologousEvent	[Reaction:R-DDI-1237042] AQP1 tetramer transports CO2 from extracellular region to cytosol - Dictyostelium discoideum [Reaction:R-PFA-1237042] AQP1 tetramer transports CO2 from extracellular region to cytosol - Plasmodium falciparum [Reaction:R-DME-1237042] AQP1 tetramer transports CO2 from extracellular region to cytosol - Drosophila melanogaster [Reaction:R-GGA-1237042] AQP1 tetramer transports CO2 from extracellular region to cytosol - Gallus gallus [Reaction:R-XTR-1237042] AQP1 tetramer transports CO2 from extracellular region to cytosol - Xenopus tropicalis [Reaction:R-DRE-1237042] AQP1 tetramer transports CO2 from extracellular region to cytosol - Danio rerio [Reaction:R-SSC-1237042] AQP1 tetramer transports CO2 from extracellular region to cytosol - Sus scrofa [Reaction:R-BTA-1237042] AQP1 tetramer transports CO2 from extracellular region to cytosol - Bos taurus [Reaction:R-CFA-1237042] AQP1 tetramer transports CO2 from extracellular region to cytosol - Canis familiaris [Reaction:R-RNO-1237042] AQP1 tetramer transports CO2 from extracellular region to cytosol - Rattus norvegicus [Reaction:R-MMU-1237042] AQP1 tetramer transports CO2 from extracellular region to cytosol - Mus musculus
output	[SimpleEntity:R-ALL-113528] CO2 [cytosol]
precedingEvent	[Reaction:R-HSA-70967] IDH3 complex decarboxylates isocitrate - Homo sapiens [Reaction:R-HSA-450984] IDH2 dimer decarboxylates isocitrate - Homo sapiens [Reaction:R-HSA-71401] OGDH dimer decarboxylates 2-OG - Homo sapiens
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2207684] Jassal, B, 2012-04-27
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1237042
summation	[Summation:1244356] Aquaporin-1 (AQP1) passively transports carbon dioxide (CO2)...

Referrals

(hasEvent)	[Pathway:R-HSA-1237044] Erythrocytes take up carbon dioxide and release oxygen
(precedingEvent)	[Reaction:R-HSA-1475435] CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- [Reaction:R-HSA-1237325] Hemoglobin A is protonated and carbamated causing release of oxygen
(reverseReaction)	[Reaction:R-HSA-1247649] AQP1 tetramer transports CO2 from cytosol to extracellular region