SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with ligand-responsive p-6Y-EGFR mutants)

authored
catalystActivity
category transition
compartment
created [InstanceEdit:1225955] Orlic-Milacic, Marija, 2011-03-03
dbId 1225951
disease
displayName SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with ligand-responsive p-6Y-EGFR mutants)
edited
entityFunctionalStatus
eventOf
input
isChimeric false
isInDisease true
isInferred false
literatureReference
modified [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name
  • SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with ligand-responsive p-6Y-EGFR mutants)
normalReaction [Reaction:R-HSA-177938] SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1)
output
precedingEvent
releaseDate 2011-12-06
reviewStatus [ReviewStatus:9821382] five stars
reviewed
schemaClass Reaction
species
stId R-HSA-1225951
summation
Cite Us!