Reactome | (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK)

Schema > Reaction > Entries

(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) Show undefined attributes

catalystActivity	[CatalystActivity:76547] adenosine kinase activity of ADK [cytosol]
catalystActivityReference	[CatalystActivityReference:9643275] adenosine kinase activity of ADK [cytosol] Purification and properties of human placental adenosine kinase
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:109609] D'Eustachio, P, 2004-01-16 17:45:00
dbId	109624
displayName	(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK)
eventOf	[Pathway:R-HSA-74217] Purine salvage - Homo sapiens
followingEvent	[Reaction:R-HSA-74220] (d)AMP + ATP <=> (d)ADP + ADP (AK1) - Homo sapiens
input	[DefinedSet:R-ALL-500173] Ade-Rib, dA [cytosol] [SimpleEntity:R-ALL-113592] ATP [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:109620] Regulation of deoxyadenosine and nucleoside analog phosphorylation by human placental adenosine kinase [LiteratureReference:109610] Effects of mutational loss of adenosine kinase and deoxycytidine kinase on deoxyATP accumulation and deoxyadenosine toxicity in cultured CEM human T-lymphoblastoid cells [LiteratureReference:76543] Structure of human adenosine kinase at 1.5 A resolution [LiteratureReference:109587] Purification and properties of human placental adenosine kinase
modified	[InstanceEdit:10901498] Wright, Adam, 2024-03-08
name	(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK)
orthologousEvent	[Reaction:R-RNO-109624] (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) - Rattus norvegicus [Reaction:R-SCE-109624] (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) - Saccharomyces cerevisiae [Reaction:R-SPO-109624] (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) - Schizosaccharomyces pombe [Reaction:R-DDI-109624] (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) - Dictyostelium discoideum [Reaction:R-CEL-109624] (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) - Caenorhabditis elegans [Reaction:R-DME-109624] (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) - Drosophila melanogaster [Reaction:R-GGA-109624] (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) - Gallus gallus [Reaction:R-XTR-109624] (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) - Xenopus tropicalis [Reaction:R-DRE-109624] (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) - Danio rerio [Reaction:R-SSC-109624] (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) - Sus scrofa [Reaction:R-BTA-109624] (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) - Bos taurus [Reaction:R-CFA-109624] (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) - Canis familiaris [Reaction:R-MMU-109624] (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) - Mus musculus
output	[DefinedSet:R-ALL-500088] (d)AMP [cytosol] [SimpleEntity:R-ALL-29370] ADP [cytosol]
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:504064] D'Eustachio, P, 2010-02-05
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-109624
summation	[Summation:178257] Cytosolic adenosine kinase (ADK) catalyzes the reactions of ...

Referrals

(hasEvent)	[Pathway:R-HSA-74217] Purine salvage
(precedingEvent)	[Reaction:R-HSA-74220] (d)AMP + ATP <=> (d)ADP + ADP (AK1)

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