Reactome | RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex

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RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex Show undefined attributes

category	transition
compartment	[Compartment:20699] Golgi membrane
created	[InstanceEdit:10560457] Wright, Adam, 2024-03-07
dbId	10634704
displayName	RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex
eventOf	[Pathway:R-GGA-6811436] COPI-independent Golgi-to-ER retrograde traffic - Gallus gallus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-GGA-8849353] Dynein drives COPI-independent retrograde traffic from the Golgi to the ER - Gallus gallus
inferredFrom	[Reaction:R-HSA-8849350] RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex - Homo sapiens
input	[Complex:R-GGA-8849246] Dynein:Dynactin:microtubules:PAFAH1B1 [cytosol] [Complex:R-GGA-8849334] RAB6:GTP:BICD dimer:COPI-independent retrograde cargo [Golgi membrane]
isInDisease	false
isInferred	true
name	RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex
output	[EntityWithAccessionedSequence:R-GGA-376249] PAFAH1B1 [cytosol] [Complex:R-GGA-8849336] RAB6:GTP:BICD dimer:COPI-independent retrograde cargo:Dynein:Dynactin:microtubules [Golgi membrane]
precedingEvent	[Reaction:R-GGA-8849348] RAB6:GTP and BICD homodimers bind COPI-independent Golgi-to-ER retrograde cargo - Gallus gallus
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-8849350
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-6811436] COPI-independent Golgi-to-ER retrograde traffic
(precedingEvent)	[BlackBoxEvent:R-GGA-8849353] Dynein drives COPI-independent retrograde traffic from the Golgi to the ER
(inferredTo)	[Reaction:R-HSA-8849350] RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex