Reactome | 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial]

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2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] Show undefined attributes

catalystActivity	[CatalystActivity:10561770] carbamoyl-phosphate synthase (ammonia) activity of CPS1 [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:10560457] Wright, Adam, 2024-03-07
dbId	10561772
displayName	2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial]
eventOf	[Pathway:R-GGA-70635] Urea cycle - Gallus gallus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-70560] carbamoyl phosphate + ornithine => citrulline + orthophosphate - Gallus gallus
inferredFrom	[Reaction:R-HSA-70555] 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] - Homo sapiens
input	2 × [SimpleEntity:R-ALL-113593] ATP [mitochondrial matrix] [SimpleEntity:R-ALL-29896] HCO3- [mitochondrial matrix] [SimpleEntity:R-ALL-113561] NH4+ [mitochondrial matrix]
isInDisease	false
isInferred	true
name	2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate
output	2 × [SimpleEntity:R-ALL-113581] ADP [mitochondrial matrix] [SimpleEntity:R-ALL-29676] CAP [mitochondrial matrix] [SimpleEntity:R-ALL-113548] Pi [mitochondrial matrix]
precedingEvent	[Reaction:R-GGA-73591] beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 - Gallus gallus
regulatedBy	[PositiveRegulation:R-HSA-70556] Positive regulation by 'NAcGlu [mitochondrial matrix]'
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-70555
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-70635] Urea cycle
(precedingEvent)	[Reaction:R-GGA-70560] carbamoyl phosphate + ornithine => citrulline + orthophosphate
(inferredTo)	[Reaction:R-HSA-70555] 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial]

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