Reactome | WNT ligand biogenesis and trafficking

Schema > Pathway > Entries

WNT ligand biogenesis and trafficking Show undefined attributes

created	[InstanceEdit:10560457] Wright, Adam, 2024-03-07
dbId	10653997
displayName	WNT ligand biogenesis and trafficking
eventOf	[Pathway:R-GGA-195721] Signaling by WNT - Gallus gallus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[BlackBoxEvent:R-GGA-3247837] WNT ligands traffic to the Golgi - Gallus gallus [Reaction:R-GGA-3247840] WLS binds WNT ligands in the Golgi - Gallus gallus [BlackBoxEvent:R-GGA-3247844] WNT ligands traffic to the plasma membrane - Gallus gallus [BlackBoxEvent:R-GGA-3781943] WLS:WNT complex is internalized for maturation into exosomes - Gallus gallus [BlackBoxEvent:R-GGA-3781941] WNTs are secreted in exosomes - Gallus gallus [Reaction:R-GGA-3247843] secretion of WNT ligands - Gallus gallus [BlackBoxEvent:R-GGA-3247847] WLS is endocytosed to the early endosome - Gallus gallus [Reaction:R-GGA-3247839] Retromer associates with WLS - Gallus gallus [BlackBoxEvent:R-GGA-3247836] Retromer recycles WLS to the Golgi - Gallus gallus [BlackBoxEvent:R-GGA-3247849] WLS dissociates from retromer - Gallus gallus
inferredFrom	[Pathway:R-HSA-3238698] WNT ligand biogenesis and trafficking - Homo sapiens
isInDisease	false
isInferred	true
name	WNT ligand biogenesis and trafficking
releaseDate	2024-03-27
schemaClass	Pathway
species	[Species:49591] Gallus gallus
stId	R-GGA-3238698
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-195721] Signaling by WNT
(hasEncapsulatedEvent)	[Pathway:R-GGA-201681] TCF dependent signaling in response to WNT
(inferredTo)	[Pathway:R-HSA-3238698] WNT ligand biogenesis and trafficking

© 2024 Reactome

Cite Us!