Reactome | DAG is acylated to TAG by DGAT1/2

Schema > Reaction > Entries

DAG is acylated to TAG by DGAT1/2 Show undefined attributes

catalystActivity	[CatalystActivity:10590741] diacylglycerol O-acyltransferase activity of DGAT2 [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:10560457] Wright, Adam, 2024-03-07
dbId	10601723
displayName	DAG is acylated to TAG by DGAT1/2
eventOf	[Pathway:R-GGA-1482883] Acyl chain remodeling of DAG and TAG - Gallus gallus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-1482777] TAG is hydrolyzed to DAG by PNPLA2/3 - Gallus gallus
inferredFrom	[Reaction:R-HSA-1482889] DAG is acylated to TAG by DGAT1/2 - Homo sapiens
input	[SimpleEntity:R-ALL-1500578] acyl-CoA [cytosol] [SimpleEntity:R-ALL-1500596] DAG [endoplasmic reticulum membrane]
isInDisease	false
isInferred	true
name	DAG is acylated to TAG by DGAT1/2
output	[SimpleEntity:R-ALL-76194] CoA-SH [cytosol] [SimpleEntity:R-ALL-1500594] TAG [endoplasmic reticulum membrane]
precedingEvent	[Reaction:R-GGA-1482777] TAG is hydrolyzed to DAG by PNPLA2/3 - Gallus gallus [Reaction:R-GGA-1482654] 2-MAG is transacylated to DAG by PNPLA2/3 - Gallus gallus [Reaction:R-GGA-5696448] AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG - Gallus gallus
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-1482889
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-1482883] Acyl chain remodeling of DAG and TAG
(precedingEvent)	[Reaction:R-GGA-1482777] TAG is hydrolyzed to DAG by PNPLA2/3
(inferredTo)	[Reaction:R-HSA-1482889] DAG is acylated to TAG by DGAT1/2