Reactome | histidine => urocanate + NH4+

Schema > Reaction > Entries

catalystActivity	[CatalystActivity:10428455] histidine ammonia-lyase activity of HAL [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10427439] Wright, Adam, 2024-03-07
dbId	10428457
displayName	histidine => urocanate + NH4+
eventOf	[Pathway:R-DRE-70921] Histidine catabolism - Danio rerio
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-DRE-70903] urocanate + H2O => 4-imidazolone-5-propionate - Danio rerio
inferredFrom	[Reaction:R-HSA-70899] histidine => urocanate + NH4+ - Homo sapiens
input	[SimpleEntity:R-ALL-29612] L-His [cytosol]
isInDisease	false
isInferred	true
name	histidine => urocanate + NH4+
output	[SimpleEntity:R-ALL-31633] NH4+ [cytosol] [SimpleEntity:R-ALL-30721] UCA [cytosol]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-70899
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-70921] Histidine catabolism
(precedingEvent)	[Reaction:R-DRE-70903] urocanate + H2O => 4-imidazolone-5-propionate
(inferredTo)	[Reaction:R-HSA-70899] histidine => urocanate + NH4+