Reactome | DENND5A,B exchange GTP for GDP on RAB39

Schema > Reaction > Entries

DENND5A,B exchange GTP for GDP on RAB39 Show undefined attributes

catalystActivity	[CatalystActivity:10727087] guanyl-nucleotide exchange factor activity of DENND5A,B [cytosol]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:70101] cytosol
created	[InstanceEdit:10655440] Wright, Adam, 2024-03-08
dbId	10727089
displayName	DENND5A,B exchange GTP for GDP on RAB39
eventOf	[Pathway:R-DME-8876198] RAB GEFs exchange GTP for GDP on RABs - Drosophila melanogaster
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8877813] DENND5A,B exchange GTP for GDP on RAB39 - Homo sapiens
input	[Complex:R-DME-8877806] GGC-RAB39:GDP:GDIs,CHMs [cytosol] [SimpleEntity:R-ALL-29438] GTP [cytosol]
isInDisease	false
isInferred	true
name	DENND5A,B exchange GTP for GDP on RAB39
output	[DefinedSet:R-DME-8875305] GDIs,CHMs [cytosol] [SimpleEntity:R-ALL-29420] GDP [cytosol] [Complex:R-DME-8877804] GGC-RAB39:GTP [Golgi membrane]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-8877813
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-8876198] RAB GEFs exchange GTP for GDP on RABs
(inferredTo)	[Reaction:R-HSA-8877813] DENND5A,B exchange GTP for GDP on RAB39

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