Reactome | Cargo recognition for clathrin-mediated endocytosis

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Cargo recognition for clathrin-mediated endocytosis Show undefined attributes

created	[InstanceEdit:10655440] Wright, Adam, 2024-03-08
dbId	10739628
displayName	Cargo recognition for clathrin-mediated endocytosis
eventOf	[Pathway:R-DME-8856828] Clathrin-mediated endocytosis - Drosophila melanogaster
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-DME-8866277] AP-2 directly binds some endocytic cargo - Drosophila melanogaster [Reaction:R-DME-9681616] AP2 binds chlorpromazine - Drosophila melanogaster [Reaction:R-DME-8866279] Epsin family proteins bind ubiquitinated cargo - Drosophila melanogaster [Reaction:R-DME-8866275] UBQLNs bind UIM-containing adaptor proteins - Drosophila melanogaster [Reaction:R-DME-8866269] ARRB bind GPCRs - Drosophila melanogaster [Reaction:R-DME-8866283] ARBB recruits GPCRs into clathrin-coated pits - Drosophila melanogaster [Reaction:R-DME-8863718] AGFG1 binds VAMP7 - Drosophila melanogaster [Reaction:R-DME-8863463] STON2 binds SYT proteins - Drosophila melanogaster [BlackBoxEvent:R-DME-8863727] STON2 is neddylated - Drosophila melanogaster [Reaction:R-DME-8863721] NEDD8-STON binds TOR1 hexamer and COP9 complex - Drosophila melanogaster [BlackBoxEvent:R-DME-8863723] COP9 and TOR1 deneddylate STON2 - Drosophila melanogaster [Reaction:R-DME-8867613] PICALM binds R-SNAREs - Drosophila melanogaster
inferredFrom	[Pathway:R-HSA-8856825] Cargo recognition for clathrin-mediated endocytosis - Homo sapiens
isInDisease	false
isInferred	true
name	Cargo recognition for clathrin-mediated endocytosis
releaseDate	2024-03-27
schemaClass	Pathway
species	[Species:56210] Drosophila melanogaster
stId	R-DME-8856825
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(inferredTo)	[Pathway:R-HSA-8856825] Cargo recognition for clathrin-mediated endocytosis
(hasEvent)	[Pathway:R-DME-8856828] Clathrin-mediated endocytosis

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