Reactome | CARKD dehydrates S-NAD(P)HX to NADPH

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CARKD dehydrates S-NAD(P)HX to NADPH Show undefined attributes

catalystActivity	[CatalystActivity:10721728] ATP-dependent NAD(P)H-hydrate dehydratase activity of CARKD [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:10655440] Wright, Adam, 2024-03-08
dbId	10721730
displayName	CARKD dehydrates S-NAD(P)HX to NADPH
eventOf	[Pathway:R-DME-197264] Nicotinamide salvaging - Drosophila melanogaster
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-6806967] CARKD dehydrates S-NAD(P)HX to NADPH - Homo sapiens
input	[SimpleEntity:R-ALL-113593] ATP [mitochondrial matrix] [SimpleEntity:R-ALL-6807477] S-NADPHX [mitochondrial matrix]
isInDisease	false
isInferred	true
name	CARKD dehydrates S-NAD(P)HX to NADPH
output	[SimpleEntity:R-ALL-113581] ADP [mitochondrial matrix] 3 × [SimpleEntity:R-ALL-113529] H+ [mitochondrial matrix] [SimpleEntity:R-ALL-113600] NADPH [mitochondrial matrix] [SimpleEntity:R-ALL-113548] Pi [mitochondrial matrix]
precedingEvent	[Reaction:R-DME-6806966] APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX - Drosophila melanogaster
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-6806967
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-197264] Nicotinamide salvaging
(inferredTo)	[Reaction:R-HSA-6806967] CARKD dehydrates S-NAD(P)HX to NADPH