Reactome | TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1

Schema > Reaction > Entries

TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1 Show undefined attributes

catalystActivity	[CatalystActivity:10714081] Lys63-specific deubiquitinase activity of TNFAIP3:K63polyUb-RIPK1 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10655440] Wright, Adam, 2024-03-08
dbId	10714083
displayName	TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1
eventOf	[Pathway:R-DME-5689896] Ovarian tumor domain proteases - Drosophila melanogaster
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-DME-5690827] TNFAIP3 (A20) ubiquitinates RIPK1 - Drosophila melanogaster
inferredFrom	[Reaction:R-HSA-5690856] TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1 - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [Complex:R-DME-6783247] TNFAIP3:K63polyUb-RIPK1 [cytosol]
isInDisease	false
isInferred	true
name	TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1
output	[Polymer:R-DME-450152] K63polyUb [cytosol] [Complex:R-DME-6783294] TNFAIP3:RIPK1 [cytosol]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-5690856
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-5689896] Ovarian tumor domain proteases
(precedingEvent)	[Reaction:R-DME-5690827] TNFAIP3 (A20) ubiquitinates RIPK1
(inferredTo)	[Reaction:R-HSA-5690856] TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1