Reactome | Canonical WNT signaling through the atypical receptor RYK

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Canonical WNT signaling through the atypical receptor RYK Show undefined attributes

category	binding
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:10655440] Wright, Adam, 2024-03-08
dbId	10707395
displayName	Canonical WNT signaling through the atypical receptor RYK
eventOf	[Pathway:R-DME-201681] TCF dependent signaling in response to WNT - Drosophila melanogaster
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5323545] Canonical WNT signaling through the atypical receptor RYK - Homo sapiens
input	[EntityWithAccessionedSequence:R-DME-3006746] RYK [plasma membrane] [DefinedSet:R-DME-5323535] RYK-binding WNTs [extracellular region]
isInDisease	false
isInferred	true
name	Canonical WNT signaling through the atypical receptor RYK
output	[Complex:R-DME-5323537] RYK:WNTs [plasma membrane]
precedingEvent	[Reaction:R-DME-3247843] secretion of WNT ligands - Drosophila melanogaster
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-5323545
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-201681] TCF dependent signaling in response to WNT
(inferredTo)	[Reaction:R-HSA-5323545] Canonical WNT signaling through the atypical receptor RYK

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