Reactome | Addition of N-acetyl-D-glucosamine to Dolichyl phosphate

Schema > Reaction > Entries

Addition of N-acetyl-D-glucosamine to Dolichyl phosphate Show undefined attributes

catalystActivity	[CatalystActivity:10680158] UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity of DPAGT1 [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:10655440] Wright, Adam, 2024-03-08
dbId	10680160
displayName	Addition of N-acetyl-D-glucosamine to Dolichyl phosphate
eventOf	[Pathway:R-DME-446193] Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein - Drosophila melanogaster
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-DME-446207] ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP - Drosophila melanogaster
inferredFrom	[Reaction:R-HSA-446191] Addition of N-acetyl-D-glucosamine to Dolichyl phosphate - Homo sapiens
input	[SimpleEntity:R-ALL-449299] DOLP [integral component of cytoplasmic side of endoplasmic reticulum membrane] [SimpleEntity:R-ALL-162756] UDP-GlcNAc [cytosol]
isInDisease	false
isInferred	true
name	Addition of N-acetyl-D-glucosamine to Dolichyl phosphate
output	[SimpleEntity:R-ALL-449222] GlcNAcDOLDP [integral component of cytoplasmic side of endoplasmic reticulum membrane] [SimpleEntity:R-ALL-109402] UMP [cytosol]
precedingEvent	[Reaction:R-DME-446204] GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine - Drosophila melanogaster [Reaction:R-DME-446195] DOLK phosphorylates DCHOL to DOLP - Drosophila melanogaster
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-446191
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-446193] Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
(precedingEvent)	[Reaction:R-DME-446207] ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP
(inferredTo)	[Reaction:R-HSA-446191] Addition of N-acetyl-D-glucosamine to Dolichyl phosphate