Reactome | Inactivation of Rac1

Schema > Reaction > Entries

authored	[InstanceEdit:376175] Garapati, P V, 2008-09-05 06:02:05
catalystActivity	[CatalystActivity:428524] GTPase activator activity of Robo:Slit:Vilse [plasma membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:428526] Garapati, P V, 2009-07-06
dbId	428520
displayName	Inactivation of Rac1
edited	[InstanceEdit:376175] Garapati, P V, 2008-09-05 06:02:05 [InstanceEdit:9010186] Orlic-Milacic, Marija, 2017-06-26
input	[SimpleEntity:R-ALL-29420] GDP [cytosol] [Complex:R-DME-428484] Rac1:GTP [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:428411] Vilse, a conserved Rac/Cdc42 GAP mediating Robo repulsion in tracheal cells and axons [LiteratureReference:428435] Cross GTPase-activating protein (CrossGAP)/Vilse links the Roundabout receptor to Rac to regulate midline repulsion
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Inactivation of Rac1
orthologousEvent	[Reaction:R-HSA-428522] Inactivation of RAC1 - Homo sapiens
output	[SimpleEntity:R-ALL-29438] GTP [cytosol] [Complex:R-DME-428485] Rac1:GDP [cytosol]
releaseDate	2009-09-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:434966] Kidd, T, 2009-08-18 [InstanceEdit:9014887] Jaworski, Alexander, 2017-07-31
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-428520
summation	[Summation:9010168] In Drosophila, Vilse binds directly to the intracellular dom...