Reactome | Gs activation by prostacyclin receptor

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Gs activation by prostacyclin receptor Show undefined attributes

catalystActivity	[CatalystActivity:10676124] guanyl-nucleotide exchange factor activity of Prostacyclin:prostacyclin receptor:Gs (inactive) [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10655440] Wright, Adam, 2024-03-08
dbId	10676126
displayName	Gs activation by prostacyclin receptor
eventOf	[Pathway:R-DME-392851] Prostacyclin signalling through prostacyclin receptor - Drosophila melanogaster
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-392870] Gs activation by prostacyclin receptor - Homo sapiens
input	[SimpleEntity:R-ALL-29438] GTP [cytosol] [Complex:R-DME-392864] Prostacyclin:prostacyclin receptor:Gs (inactive) [plasma membrane]
isInDisease	false
isInferred	true
name	Gs activation by prostacyclin receptor
output	[SimpleEntity:R-ALL-114549] GDP [plasma membrane] [Complex:R-DME-392865] Prostacyclin:prostacyclin receptor:G-protein Gs (active) [plasma membrane]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-392870
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-392851] Prostacyclin signalling through prostacyclin receptor
(inferredTo)	[Reaction:R-HSA-392870] Gs activation by prostacyclin receptor

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