Reactome | Addition of nucleotides leads to transcript elongation

Schema > Reaction > Entries

Addition of nucleotides leads to transcript elongation Show undefined attributes

category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10655440] Wright, Adam, 2024-03-08
dbId	10662851
displayName	Addition of nucleotides leads to transcript elongation
eventOf	[Pathway:R-DME-75955] RNA Polymerase II Transcription Elongation - Drosophila melanogaster
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-DME-113412] Pol II elongation complex moves on the template as transcript elongates - Drosophila melanogaster [Reaction:R-DME-113411] 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing - Drosophila melanogaster [Reaction:R-DME-113414] 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest - Drosophila melanogaster
inferredFrom	[Reaction:R-HSA-112385] Addition of nucleotides leads to transcript elongation - Homo sapiens
input	[Complex:R-DME-112433] Elongation complex [nucleoplasm] [SimpleEntity:R-ALL-9757634] NTP [nucleoplasm]
isInDisease	false
isInferred	true
name	Addition of nucleotides leads to transcript elongation
output	[Complex:R-DME-113719] Processive elongation complex [nucleoplasm] [Complex:R-DME-109634] TFIIH [nucleoplasm]
precedingEvent	[Reaction:R-DME-112379] Recruitment of elongation factors to form elongation complex - Drosophila melanogaster
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-112385
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-75955] RNA Polymerase II Transcription Elongation
(precedingEvent)	[Reaction:R-DME-113412] Pol II elongation complex moves on the template as transcript elongates [Reaction:R-DME-113411] 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing [Reaction:R-DME-113414] 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest
(inferredTo)	[Reaction:R-HSA-112385] Addition of nucleotides leads to transcript elongation