Reactome | Cho transports from the extracellular space to the cytosol

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Cho transports from the extracellular space to the cytosol Show undefined attributes

catalystActivity	[CatalystActivity:10833865] choline transmembrane transporter activity of CTL1-5 [plasma membrane]
category	transition
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:10818988] Wright, Adam, 2024-03-08
dbId	10833867
displayName	Cho transports from the extracellular space to the cytosol
eventOf	[Pathway:R-DDI-1483191] Synthesis of PC - Dictyostelium discoideum [Pathway:R-DDI-425366] Transport of bile salts and organic acids, metal ions and amine compounds - Dictyostelium discoideum
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-DDI-6797956] SLC44A1 transports Cho from cytosol to mitochondrial matrix - Dictyostelium discoideum
inferredFrom	[Reaction:R-HSA-444433] Cho transports from the extracellular space to the cytosol - Homo sapiens
input	[SimpleEntity:R-ALL-264638] Cho [extracellular region]
isInDisease	false
isInferred	true
name	Cho transports from the extracellular space to the cytosol CTL1-5 can mediate the uptake of choline
output	[SimpleEntity:R-ALL-264618] Cho [cytosol]
precedingEvent	[Reaction:R-DDI-372519] AcCho is hydrolyzed to Cho and acetate by ACHE - Dictyostelium discoideum
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-444433
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DDI-1483191] Synthesis of PC [Pathway:R-DDI-425366] Transport of bile salts and organic acids, metal ions and amine compounds
(precedingEvent)	[Reaction:R-DDI-6797956] SLC44A1 transports Cho from cytosol to mitochondrial matrix
(inferredTo)	[Reaction:R-HSA-444433] Cho transports from the extracellular space to the cytosol

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