Reactome | PKMTs methylate histone lysines

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PKMTs methylate histone lysines Show undefined attributes

created	[InstanceEdit:10818988] Wright, Adam, 2024-03-08
dbId	10870142
displayName	PKMTs methylate histone lysines
eventOf	[Pathway:R-DDI-3247509] Chromatin modifying enzymes - Dictyostelium discoideum
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DDI-5159245] SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) - Dictyostelium discoideum [Reaction:R-DDI-5637686] WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) - Dictyostelium discoideum [Reaction:R-DDI-5244692] Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) - Dictyostelium discoideum [Reaction:R-DDI-4827382] SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) - Dictyostelium discoideum [Reaction:R-DDI-5638333] WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) - Dictyostelium discoideum [Reaction:R-DDI-5649800] WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) - Dictyostelium discoideum [Reaction:R-DDI-5649802] WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) - Dictyostelium discoideum [Reaction:R-DDI-4827383] WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) - Dictyostelium discoideum [Reaction:R-DDI-5638157] WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) - Dictyostelium discoideum [Reaction:R-DDI-5649801] DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) - Dictyostelium discoideum [Reaction:R-DDI-5649764] DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) - Dictyostelium discoideum [Reaction:R-DDI-5649799] DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) - Dictyostelium discoideum
inferredFrom	[Pathway:R-HSA-3214841] PKMTs methylate histone lysines - Homo sapiens
isInDisease	false
isInferred	true
name	PKMTs methylate histone lysines
releaseDate	2024-03-27
schemaClass	Pathway
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-3214841
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DDI-3247509] Chromatin modifying enzymes
(inferredTo)	[Pathway:R-HSA-3214841] PKMTs methylate histone lysines

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