Reactome | Abacavir metabolism

Schema > Pathway > Entries

created	[InstanceEdit:10818988] Wright, Adam, 2024-03-08
dbId	10870002
displayName	Abacavir metabolism
eventOf	[Pathway:R-DDI-2161522] Abacavir ADME - Dictyostelium discoideum
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:8764] xenobiotic metabolic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DDI-2162078] abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ - Dictyostelium discoideum [Reaction:R-DDI-2162066] carbovir + IMP => carbovir monophosphate + inosine - Dictyostelium discoideum
inferredFrom	[Pathway:R-HSA-2161541] Abacavir metabolism - Homo sapiens
isInDisease	false
isInferred	true
name	Abacavir metabolism
releaseDate	2024-03-27
schemaClass	Pathway
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-2161541
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DDI-2161522] Abacavir ADME
(inferredTo)	[Pathway:R-HSA-2161541] Abacavir metabolism