Reactome | Phosphopantetheine conjugation of the ACP domain of FAS

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Phosphopantetheine conjugation of the ACP domain of FAS Show undefined attributes

catalystActivity	[CatalystActivity:10828549] holo-[acyl-carrier-protein] synthase activity of AASDHPPT [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10818988] Wright, Adam, 2024-03-08
dbId	10828551
displayName	Phosphopantetheine conjugation of the ACP domain of FAS
eventOf	[Pathway:R-DDI-199220] Vitamin B5 (pantothenate) metabolism - Dictyostelium discoideum
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-199202] Phosphopantetheine conjugation of the ACP domain of FAS - Homo sapiens
input	[SimpleEntity:R-ALL-76194] CoA-SH [cytosol] [DefinedSet:R-DDI-199233-4] Homologues of FASN [cytosol]
isInDisease	false
isInferred	true
name	Phosphopantetheine conjugation of the ACP domain of FAS CoA-SH + FAS apoenzyme => adenosine 3',5'-bisphosphate + FAS holoenzyme
output	[DefinedSet:R-DDI-54659-4] Homologues of FASN [cytosol] [SimpleEntity:R-ALL-158466] PAP [cytosol]
precedingEvent	[Reaction:R-DDI-196773] COASY phosphorylates DP-CoA - Dictyostelium discoideum
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-199202
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DDI-199220] Vitamin B5 (pantothenate) metabolism
(inferredTo)	[Reaction:R-HSA-199202] Phosphopantetheine conjugation of the ACP domain of FAS

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