Reactome | Synthesis of glycosylphosphatidylinositol (GPI)

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Synthesis of glycosylphosphatidylinositol (GPI) Show undefined attributes

created	[InstanceEdit:10818988] Wright, Adam, 2024-03-08
dbId	10869168
displayName	Synthesis of glycosylphosphatidylinositol (GPI)
eventOf	[Pathway:R-DDI-163125] Post-translational modification: synthesis of GPI-anchored proteins - Dictyostelium discoideum
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:24418] preassembly of GPI anchor in ER membrane
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DDI-162857] N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate - Dictyostelium discoideum [Reaction:R-DDI-162683] glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH - Dictyostelium discoideum [Reaction:R-DDI-162830] glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate - Dictyostelium discoideum [Reaction:R-DDI-162798] mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol - Dictyostelium discoideum [Reaction:R-DDI-162873] (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate - Dictyostelium discoideum [Reaction:R-DDI-162821] mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate - Dictyostelium discoideum [Reaction:R-DDI-162797] mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI - Dictyostelium discoideum [Reaction:R-DDI-162742] (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> (ethanolamineP) mannose (a1-2) (ethanolamineP) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI - Dictyostelium discoideum
inferredFrom	[Pathway:R-HSA-162710] Synthesis of glycosylphosphatidylinositol (GPI) - Homo sapiens
isInDisease	false
isInferred	true
name	Synthesis of glycosylphosphatidylinositol (GPI)
releaseDate	2024-03-27
schemaClass	Pathway
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-162710
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DDI-163125] Post-translational modification: synthesis of GPI-anchored proteins
(inferredTo)	[Pathway:R-HSA-162710] Synthesis of glycosylphosphatidylinositol (GPI)

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