Reactome | SPT5 subunit of Pol II binds the RNA triphosphatase (RTP)

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SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10098795] Wright, Adam, 2024-03-07
dbId	10105175
displayName	SPT5 subunit of Pol II binds the RNA triphosphatase (RTP)
eventOf	[Pathway:R-CFA-77075] RNA Pol II CTD phosphorylation and interaction with CE - Canis familiaris [Pathway:R-CFA-72086] mRNA Capping - Canis familiaris
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-77077] Capping complex formation - Canis familiaris
inferredFrom	[Reaction:R-HSA-77073] SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) - Homo sapiens
input	[EntityWithAccessionedSequence:R-CFA-3009372] phospho-SUPT5H [nucleoplasm] [Complex:R-CFA-77053] RNA Pol II with phosphorylated CTD: CE complex [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-77060] RNMT [nucleoplasm]
isInDisease	false
isInferred	true
name	SPT5 subunit of Pol II binds the RNA triphosphatase (RTP)
output	[Complex:R-CFA-77061] CE:Pol II CTD:Spt5 complex [nucleoplasm]
precedingEvent	[Reaction:R-CFA-77068] Activation of GT - Canis familiaris
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-77073
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-72086] mRNA Capping [Pathway:R-CFA-77075] RNA Pol II CTD phosphorylation and interaction with CE
(precedingEvent)	[Reaction:R-CFA-77077] Capping complex formation
(inferredTo)	[Reaction:R-HSA-77073] SPT5 subunit of Pol II binds the RNA triphosphatase (RTP)