Reactome | thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1]

Schema > Reaction > Entries

thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] Show undefined attributes

catalystActivity	[CatalystActivity:10102925] nucleoside kinase activity of TK1 tetramer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10098795] Wright, Adam, 2024-03-07
dbId	10102927
displayName	thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1]
eventOf	[Pathway:R-CFA-73614] Pyrimidine salvage - Canis familiaris
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-73635] dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] - Canis familiaris
inferredFrom	[Reaction:R-HSA-73632] thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-83928] Thy-dRib [cytosol]
isInDisease	false
isInferred	true
name	thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] phosphorylation of 2'-Deoxythymidine to dTMP
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-109366] TMP [cytosol]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-73632
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-73614] Pyrimidine salvage
(precedingEvent)	[Reaction:R-CFA-73635] dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK]
(inferredTo)	[Reaction:R-HSA-73632] thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1]

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