Reactome | Pyrimidine catabolism

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Pyrimidine catabolism Show undefined attributes

created	[InstanceEdit:10098795] Wright, Adam, 2024-03-07
dbId	10199882
displayName	Pyrimidine catabolism
eventOf	[Pathway:R-CFA-8956319] Nucleotide catabolism - Canis familiaris
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:6248] pyrimidine nucleoside catabolic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-CFA-109514] TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] - Canis familiaris [Reaction:R-CFA-109291] CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] - Canis familiaris [Reaction:R-CFA-109449] (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) - Canis familiaris [Reaction:R-CFA-109380] (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) - Canis familiaris [Reaction:R-CFA-109480] TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] - Canis familiaris [Reaction:R-CFA-74376] (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) - Canis familiaris [Reaction:R-CFA-73585] uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ - Canis familiaris [Reaction:R-CFA-73589] 5,6-dihydrouracil + H2O => beta-ureidopropionate - Canis familiaris [Reaction:R-CFA-73591] beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 - Canis familiaris [Reaction:R-CFA-73616] thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ - Canis familiaris [Reaction:R-CFA-73618] 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate - Canis familiaris [Reaction:R-CFA-73620] beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 - Canis familiaris
inferredFrom	[Pathway:R-HSA-73621] Pyrimidine catabolism - Homo sapiens
isInDisease	false
isInferred	true
name	Pyrimidine catabolism
releaseDate	2024-03-27
schemaClass	Pathway
species	[Species:49646] Canis familiaris
stId	R-CFA-73621
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-8956319] Nucleotide catabolism
(inferredTo)	[Pathway:R-HSA-73621] Pyrimidine catabolism

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