Reactome | Dual incision in TC-NER

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Dual incision in TC-NER Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10098795] Wright, Adam, 2024-03-07
dbId	10202452
displayName	Dual incision in TC-NER
eventOf	[Pathway:R-CFA-6781827] Transcription-Coupled Nucleotide Excision Repair (TC-NER) - Canis familiaris
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Pathway:R-CFA-6782210] Gap-filling DNA repair synthesis and ligation in TC-NER - Canis familiaris
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-CFA-6782131] ERCC2-facilitated RNA Pol II backtracking in TC-NER - Canis familiaris [Reaction:R-CFA-9684118] ERCC3-facilitated RNA Pol II backtracking in TC-NER - Canis familiaris [Reaction:R-CFA-6782138] ERCC5 and RPA bind TC-NER site - Canis familiaris [Reaction:R-CFA-6782141] Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER - Canis familiaris [Reaction:R-CFA-6782204] 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER - Canis familiaris [Reaction:R-CFA-6782211] DNA polymerases delta, epsilon or kappa bind the TC-NER site - Canis familiaris [Reaction:R-CFA-6782224] 3' incision by ERCC5 (XPG) in TC-NER - Canis familiaris
inferredFrom	[Pathway:R-HSA-6782135] Dual incision in TC-NER - Homo sapiens
isInDisease	false
isInferred	true
name	Dual incision in TC-NER
precedingEvent	[Pathway:R-CFA-6781823] Formation of TC-NER Pre-Incision Complex - Canis familiaris
releaseDate	2024-03-27
schemaClass	Pathway
species	[Species:49646] Canis familiaris
stId	R-CFA-6782135
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-6781827] Transcription-Coupled Nucleotide Excision Repair (TC-NER)
(precedingEvent)	[Pathway:R-CFA-6782210] Gap-filling DNA repair synthesis and ligation in TC-NER
(inferredTo)	[Pathway:R-HSA-6782135] Dual incision in TC-NER