Reactome | B-WICH complex binds rDNA promoter

Schema > Reaction > Entries

B-WICH complex binds rDNA promoter Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10098795] Wright, Adam, 2024-03-07
dbId	10161806
displayName	B-WICH complex binds rDNA promoter
eventOf	[Pathway:R-CFA-5250924] B-WICH complex positively regulates rRNA expression - Canis familiaris
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-5250930] B-WICH recruits histone acetyltransferases - Canis familiaris
inferredFrom	[Reaction:R-HSA-5250947] B-WICH complex binds rDNA promoter - Homo sapiens
input	[EntityWithAccessionedSequence:R-CFA-417153] BAZ1B [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-5250652] DDX21 [nucleoplasm] [Complex:R-CFA-5365864] ERCC6 dimer [nucleoplasm] [DefinedSet:R-CFA-5250643-3] Homologues of DEK [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-5250650] MYBBP1A [nucleoplasm] [Complex:R-CFA-5250916] MYO1C:ACTB [nucleoplasm] [OtherEntity:R-ALL-73682] rDNA Promoter [nucleoplasm] [Complex:R-CFA-73859] RNA Polymerase I Holoenzyme [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-71968] SF3B1 [nucleoplasm] [Complex:R-CFA-73692] SL1 [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-417140] SMARCA5 [nucleoplasm]
isInDisease	false
isInferred	true
name	B-WICH complex binds rDNA promoter
output	[EntityWithAccessionedSequence:R-CFA-3321990] ACTB [nucleoplasm] [Complex:R-CFA-5250923] B-WICH:rDNA Promoter:SL1:RNA Pol I [nucleoplasm]
regulatedBy	[PositiveRegulation:10161807] Positive regulation by 'GSK3B [nucleoplasm]'
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-5250947
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-5250924] B-WICH complex positively regulates rRNA expression
(precedingEvent)	[Reaction:R-CFA-5250930] B-WICH recruits histone acetyltransferases
(inferredTo)	[Reaction:R-HSA-5250947] B-WICH complex binds rDNA promoter