Reactome | WNT5A binding to FZD promotes PRICKLE1 degradation

Schema > Reaction > Entries

WNT5A binding to FZD promotes PRICKLE1 degradation Show undefined attributes

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:10098795] Wright, Adam, 2024-03-07
dbId	10160206
displayName	WNT5A binding to FZD promotes PRICKLE1 degradation
eventOf	[Pathway:R-CFA-4608870] Asymmetric localization of PCP proteins - Canis familiaris
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5099886] WNT5A binding to FZD promotes PRICKLE1 degradation - Homo sapiens
input	[EntityWithAccessionedSequence:R-CFA-3247777] WNT5A [extracellular region] [CandidateSet:R-CFA-5140744] WNT5A-binding FZDs [plasma membrane]
isInDisease	false
isInferred	true
name	WNT5A binding to FZD promotes PRICKLE1 degradation
output	[Complex:R-CFA-4608830] WNT5A:FZD [plasma membrane]
precedingEvent	[Reaction:R-CFA-3247843] secretion of WNT ligands - Canis familiaris
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-5099886
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-4608870] Asymmetric localization of PCP proteins
(inferredTo)	[Reaction:R-HSA-5099886] WNT5A binding to FZD promotes PRICKLE1 degradation

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