Reactome | PDE6 hydrolyses cGMP to GMP

Schema > Reaction > Entries

catalystActivity	[CatalystActivity:10159319] 3',5'-cyclic-GMP phosphodiesterase activity of GNAT2:PDE6 [plasma membrane]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10098795] Wright, Adam, 2024-03-07
dbId	10159321
displayName	PDE6 hydrolyses cGMP to GMP
eventOf	[Pathway:R-CFA-4086398] Ca2+ pathway - Canis familiaris
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-4086392] PDE6 hydrolyses cGMP to GMP - Homo sapiens
input	[SimpleEntity:R-ALL-30991] cGMP [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	true
name	PDE6 hydrolyses cGMP to GMP
output	[SimpleEntity:R-ALL-113578] GMP [cytosol]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-4086392
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CFA-4086398] Ca2+ pathway
(inferredTo)	[Reaction:R-HSA-4086392] PDE6 hydrolyses cGMP to GMP