Reactome | ABCG5:ABCG8 transports sterols from cytosol to extracellular region

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ABCG5:ABCG8 transports sterols from cytosol to extracellular region Show undefined attributes

catalystActivity	[CatalystActivity:10121057] sterol transporter activity of ABCG5:ABCG8 [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:10098795] Wright, Adam, 2024-03-07
dbId	10121059
displayName	ABCG5:ABCG8 transports sterols from cytosol to extracellular region
eventOf	[Pathway:R-CFA-1369062] ABC transporters in lipid homeostasis - Canis familiaris
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-265783] ABCG5:ABCG8 transports sterols from cytosol to extracellular region - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol] [DefinedSet:R-ALL-265784] sterols [cytosol]
isInDisease	false
isInferred	true
name	ABCG5:ABCG8 transports sterols from cytosol to extracellular region ABCG5:ABCG8-mediated export of cholesterol and phytosterols sterols[cytosol] + ATP => sterols[extracellular] + ADP + Pi
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-29372] Pi [cytosol] [DefinedSet:R-ALL-265781] sterols [extracellular region]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-265783
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-1369062] ABC transporters in lipid homeostasis
(inferredTo)	[Reaction:R-HSA-265783] ABCG5:ABCG8 transports sterols from cytosol to extracellular region

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